A population-based study of Kaposi Sarcomaassociated herpesvirus seropositivity in Uganda using principal components analysis

Table 2 Seroprevalence and association between KSHV seropositivity and Principal components (PCs) by quartile

Principal components	KSHV seropositivity		Univariate		Multivariable^a		Full multivariable model^b
	%	95% CI	OR	95% CI	OR	95% CI	OR	95% CI
Sexual behavioral
1^st quartile	49.2	50.0, 54.4	Ref	Ref	Ref	Ref	Ref	Ref
2^nd quartile	56.6	51.5, 61.6	1.35	1.01, 1.80	1.11	0.82, 1.51	1.08	0.79, 1.46
3^rd quartile	56.7	51.9, 61.7	1.36	1.02, 1.80	1.06	0.77, 1.45	1.02	0.73, 1.42
4^th quartile	56.2	51.5, 60.9	1.33	1.01, 1.73	0.95	0.69, 1.32	0.96	0.68, 1.35
P value for heterogeneity	0.106		0.10		0.74		0.89
P value for trend			0.066		0.61		0.58
Socioeconomic
1^st quartile	61.6	57.3, 65.9	Ref	Ref	Ref	Ref	Ref	Ref
2^nd quartile	56.8	52.2, 61.4	0.82	0.65, 1.05	0.85	0.67, 1.08	0.87	0.67, 1.14
3^rd quartile	48.8	43.7, 53.9	0.60	0.46, 0.78	0.61	0.47, 0.81	0.68	0.49, 0.92
4^th quartile	50.6	45.4, 55.8	0.64	0.49, 0.84	0.67	0.50, 0.91	0.78	0.54, 1.13
P value for heterogeneity	0.0003*		0.0004*		0.005		0.095
P value for trend			0.0001*		0.002*		0.037*
Knowledge
1^st quartile	59.9	55.5, 64.4	Ref	Ref	Ref	Ref	Ref	Ref
2^nd quartile	55.5	50.0, 60.9	0.83	0.63, 1.11	0.85	0.64, 1.14	1.00	0.74, 1.36
3^rd quartile	47.7	42.8, 52.5	0.61	0.47, 0.79	0.63	0.48, 0.82	0.76	0.57, 1.02
4^th quartile	54.4	49.8, 58.9	0.80	0.62, 1.02	0.80	0.63, 1.03	0.96	0.74, 1.25
P value for heterogeneity	0.004*		0.003*		0.006*		0.18
P value for trend			0.012*		0.018*		0.49

^a. Adjusted for age, sex, geographical region; ^b. Adjusted for age, sex, and geographical region and other PCs; * p-value < 0.0.

ISSN: 1750-9378