Table 1 Relative contribution of HPV 16/18/31/33/45/52/58 in cases of ICC HPV-positive, by region
From: Potential impact of a nine-valent vaccine in human papillomavirus related cervical disease
World | Africa | Asia | Western/ Central Asia | Eastern Asia | Latin America | South America | Central America | North America | Europe | Oceania | |
|---|---|---|---|---|---|---|---|---|---|---|---|
(n = 8,977) | (n = 544) | (n = 2,641) | (n = 836) | (n = 1,805) | (n = 3,404) | (n = 2,629) | (n = 775) | (n = 160) | (n = 2,058) | (n = 170) | |
RC % (95%CI) | RC % (95%CI) | RC % (95%CI) | RC % (95%CI) | RC % (95%CI) | RC % (95%CI) | RC % (95%CI) | RC % (95%CI) | RC % (95%CI) | RC % (95%CI) | RC % (95%CI) | |
Combinations of HPV types | |||||||||||
9 HPV types* | 89.4 (88.8-90.1) | 86.9 (83.8-89.7) | 91.5 (90.4-92.5) | 92.0 (89.9-93.7) | 91.3 (89.9-92.6) | 88.2 (87.0-89.2) | 89.2 (87.9-90.3) | 84.6 (81.9-87.1) | 95.5 (91.2-98.2) | 89.1 (87.7-90.4) | 89.4 (83.8-93.6) |
16/18 | 70.8 (69.8-71.7) | 70.3 (66.2-74.0) | 71.6 (69.8-73.4) | 77.5 (74.5-80.3) | 68.9 (66.7-71.1) | 68.2 (66.6-69.8) | 69.4 (67.6-71.1) | 64.4 (60.9-67.8) | 78.8 (71.6-84.8) | 72.8 (70.8-74.7) | 78.2 (71.3-84.2) |
31/33/45/52/58 | 18.5 (17.7-19.3) | 16.7 (13.7-20.1) | 19.8 (18.3-21.3) | 14.5 (12.2-17.0) | 22.3 (20.4-24.3) | 19.8 (18.5-21.2) | 19.6 (18.1-21.2) | 20.3 (17.5-23.3) | 16.9 (11.4-23.6) | 16.2 (14.6-17.8) | 8.8 (5.0-14.1) |
Other Types | 10.6 (9.9-11.2) | 13.0 (10.3-16.2) | 8.5 (7.5-9.6) | 8.0 (6.3-10.1) | 8.7 (7.4-10.1) | 11.8 (10.8-13.0) | 10.9 (9.7-12.1) | 15.4 (12.9-18.1) | 4.6 (1.8-8.8) | 10.9 (9.6-12.3) | 10.6 (6.4-16.2) |
Specific HPV types | |||||||||||
16 | 60.5 (59.5-61.6) | 47.7 (43.3-51.9) | 60.5 (58.6-62.3) | 66.7 (63.3-69.8) | 57.6 (55.3-59.9) | 59.2 (57.5-70.9) | 61.3 (59.4-63.2) | 52.0 (48.4-55.6) | 71.9 (64.2-78.9) | 65.5 (63.4-67.6) | 58.6 (51.0-66.3) |
18 | 10.3 (9.6-10.9) | 22.6 (19.2-26.4) | 11.2 (10.0-12.4) | 10.8 (8.9-13.2) | 11.3 (9.9-12.9) | 9.1 (8.1-10.1) | 8.1 (7.1-9.2) | 12.5 (10.3-15.1) | 6.9 (3.48-11.8) | 7.3 (6.2-8.5) | 19.9 (14.3-26.8) |
31 | 3.7 (3.3-4.1) | 1.9 (0.9-3.4) | 3.0 (2.4-3.8) | 2.8 (1.6-4.0) | 3.2 (2.4-4.1) | 4.9 (4.2-5.7) | 6.5 (5.6-7.6) | 4.3 (3.0-5.9) | 3.4 (1.0-7.1) | 3.4 (2.7-4.3) | 0.7 (0.0-3.2) |
33 | 3.8 (3.4-4.3) | 1.5 (0.6-2.9) | 3.5 (2.8-4.3) | 2.5 (1.6-3.8) | 4.0 (3.1-4.9) | 3.5 (3.2-4.5) | 5.0 (4.3-6.0) | 2.9 (1.9-4.4) | 3.1 (1.0-7.1) | 5.7 (4.7-6.8) | 2.1 (0.4-5.1) |
45 | 5.9 (5.4-6.4) | 9.9 (7.6-12.8) | 5.5 (4.7-6.5) | 7.0 (5.4-9.0) | 4.9 (3.9-6.0) | 6.8 (5.9-7.7) | 3.7 (3.0-4.4) | 7.5 (5.7-9.6) | 5.4 (2.6-10.4) | 3.9 (3.1-4.8) | 5.5 (2.5-9.8) |
52 | 2.8 (2.5-3.2) | 2.6 (1.4-4.3) | 3.8 (3.1-4.6) | 0.8 (0.3-1.7) | 5.3 (4.3-6.4) | 2.7 (2.2-3.3) | 3.0 (2.4-3.7) | 1.6 (0.9-2.9) | 2.9 (1.0-7.1) | 1.9 (1.4-2.6) | 0.6 (0.0-3.2) |
58 | 2.3 (2.0-2.6) | 0.7 (0.2-1.9) | 3.9 (3.2-4.7) | 1.3 (0.7-2.3) | 5.0 (4.1-6.2) | 2.0 (3.3-2.5) | 1.4 (1.0-2.0) | 3.9 (2.6-5.5) | 1.9 (0.39-5.4) | 1.3 (0.9-1.9) | 0.0 (0.0-2.2) |
6 | 0.1 (0.1-0.2) | 0.0 (0.0-0.7) | 0.0 (0.0-0.2) | 0.0 (0.0-0.4) | 0.1 (0.0-0.3) | 0.1 (0.0-0.3) | 0.1 (0.0-0.3) | 0.0 (0.0-0.5) | 0.0 (0.0-2.3) | 0.2 (0.0-0.4) | 1.8 (0.4-5.1) |
11 | 0.0 (0.0-0.1) | 0.0 (0.0-0.7) | 0.0 (0.0-0.2) | 0.0 (0.0-0.4) | 0.1 (0.0-0.3) | 0.0 (0.0-0.2) | 0.0 (0.0-0.2) | 0.0 (0.0-0.5) | 0.0 (0.0-2.3) | 0.0 (0.0-0.2) | 0.0 (0.0-2.2) |