Figure 3

Relative contribution of HPV 16/18/45/31/33/52/58 in precancerous cervical lesions HPV-positive, by histological and cytological diagnosis. “CIN1”: Cervical intraepithelial neoplasia grade 1; “CIN2”: Cervical intraepithelial neoplasia grade 2; “CIN3”: Cervical intraepithelial neoplasia grade 3 (including squamous carcinoma in situ); “ASCUS”: Atypical squamous cells of undetermined significance; “LSIL”: Low-grade squamous intraepithelial lesion; “HSIL”: High-grade squamous intraepithelial lesion; “RC”: Relative Contribution; “95%CI”: 95% Confidence Interval. Additional information: HPV type specific relative contribution: Numerator = includes either single or multiple infections, thus the total sum of % can exceed 100%; Denominator = ”Tested” cases that stands for the HPV/DNA positive cases from studies testing for the HPV type in question, thus denominators vary by type. The data source does not give specific information for HPV 6 and 11. 17. Data from Guan et al., IJC, 2012.