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Figure 2 | Infectious Agents and Cancer

Figure 2

From: Toll-like receptor 3 in Epstein-Barr virus-associated nasopharyngeal carcinomas: consistent expression and cytotoxic effects of its synthetic ligand poly(A:U) combined to a Smac-mimetic

Figure 2

TLR3 is consistently detected by immunohistochemistry on tissue sections from NPC biopsies. (A) C666-1 and NP69 cell pellets were used as positive and negative controls for TLR3 immunostaining, respectively; note the strong juxtanuclear staining in C666-1 cells (suggestive of endosomal TLR3 localization) and the low level of staining in NP69 cells, consistent with western blot data displayed in figure1C. (B,C) NPC biopsy sections (B = patient#6; C = patient#8) were stained with hematoxilin and eosin safran (HES), or immunostained with antihuman TLR3 antibody (40 F9.6, Innate Pharma, Marseille). TLR3 was detected in all biopsies in a substantial fraction of cells, although with heterogeneous levels of intensity.

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Infectious Agents and Cancer

ISSN: 1750-9378

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