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Figure 1 | Infectious Agents and Cancer

Figure 1

From: Toll-like receptor 3 in Epstein-Barr virus-associated nasopharyngeal carcinomas: consistent expression and cytotoxic effects of its synthetic ligand poly(A:U) combined to a Smac-mimetic

Figure 1

TLR3 is highly expressed in NPC cell lines and xenografts. Western blot analysis reveals intense expression of TLR3 in EBV-positive C666-1, C18, C17 and C15 xenografts/cell lines (A), and in EBV-negative HONE1 and CNE1 NPC cell lines (B). To better characterize the status of TLR3 in NPC cells, its expression was simultaneously assessed in C666-1, in the non NPC head and neck squamous cell carcinoma cell lines SQ20B and FaDu, and in a panel of non malignant and malignant epithelial cell-lines, namely NP69 and NP460 (non tumorigenic immortalized nasopharyngeal cell lines), HeLa, C33 and CaSki (cervical carcinoma), SW613 (colon carcinoma), A549 (non-small cell lung cancer), and A431 (vulvar squamous carcinoma) (C). The same blotted membranes were stained with anti-actin for protein loading controls.

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Infectious Agents and Cancer

ISSN: 1750-9378

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