|
(−592 C/A) (rs1800872)
|
(−819 C/T) (rs1800871)
|
|---|
|
Genotype
|
n(%)SICL/(%)NCL (n = 204/166)
|
ORa (IC95%)
|
p Value*
|
Genotype
|
n(%)SICL/(%)NCL (n = 204/166)
|
ORa (IC95%)
|
p Value*
|
|---|
|
Codominant Model
|
Codominant Model
|
|
C/C
|
50(24.5)/66(40)
|
1
|
C/C
|
64(31.4)/57(34.3)
|
1
|
|
C/A
|
105(52)/70(42)
|
2.0(1.21-3.32)
|
0.007
|
C/T
|
94(46)/75(45.2)
|
1.16(0.71-1.92)
|
0.53
|
|
A/A
|
49(24)/30(18)
|
2.07(1.10-3.89)
|
0.02
|
T/T
|
46(22.6)/34(20.5)
|
1.15(0.62-2.12)
|
0.64
|
|
Dominant Model
|
Dominant Model
|
|
C/C
|
50(24.5)/66(40)
|
1
|
C/C
|
64(31.4)/57(34.3)
|
1
|
|
C/A + A/A
|
154(76)/100(60)
|
2.02(1.26-3.25)
|
0.003
|
C/T + T/T
|
140(68.5)/109(65.7)
|
1.16(0.73-1.84)
|
0.51
|
|
Recessive Model
|
Recessive Model
|
|
C/C + C/A
|
155(76)/136(82)
|
1
|
C/C + C/T
|
158(77.4)/132(79.5)
|
1
|
|
A/A
|
49(24)/30(18)
|
1.37(0.79-2.39)
|
0.25
|
T/T
|
46(22.6)/34(20.5)
|
1.05(0.61-1.81)
|
0.84
|
|
Alleles
|
Alleles
|
|
C
|
205(51)/202(60)
|
1
|
C
|
222(54)/189(57)
|
1
|
|
A
|
203(49)/130(40)
|
1.32 (0.97-1.81)
|
0.07
|
T
|
186(46)/143(43)
|
1.10(0.80-1.50)
|
0.53
|
|
p HWE**
|
0.13
|
p HWE**
|
0.31
|
|
(−1082 A/G) (rs1800872)
|
(−1352 G/A) (rs1800893)
|
|
Genotype
|
n(%)SICL/(%)NCL (n = 204/166)
|
OR a (IC95%)
|
p Value*
|
Genotype
|
n(%)SICL/(%)NCL (n = 204/166)
|
OR a (IC95%)
|
p Value*
|
|
Codominant Model
|
Codominant Model
|
|
A/A
|
125(61.3)/92(55.4)
|
1
|
G/G
|
130(63.72)/102(61.44)
|
1
|
|
A/G
|
66(32.3)/62(37.3)
|
0.95(0.59-1.52)
|
0.84
|
G/A
|
64(31.37)/53(31.94)
|
1.28(0.78-2.07)
|
0.31
|
|
G/G
|
13(6.4/12(7.3)
|
1.02(0.42-2.44)
|
0.96
|
A/A
|
10(4.9)/11(6.62)
|
0.85(0.33-2.22)
|
0.75
|
|
Dominant Model
|
Dominant Model
|
|
A/A
|
125(61.3)/92(55.4)
|
1
|
G/G
|
130(63.72)/102(61.44)
|
1
|
|
A/G + G/G
|
79(38.7)/74(44.6)
|
0.96(0.61-1.50)
|
0.87
|
G/A + A/A
|
74(36.27)/64(38.56)
|
1.20(0.76-1.90)
|
0.42
|
|
Recessive Model
|
Recessive Model
|
|
A/A + A/G
|
191(93.6)/154(92.7)
|
1
|
G/G + G/A
|
194(95)/155(93.38)
|
1
|
|
G/G
|
13(6.4/12(7.3)
|
1.04(0.44-2.44)
|
0.92
|
A/A
|
10(4.9)/11(6.62)
|
0.78(0.30-1.99)
|
0.6
|
|
Alleles
|
Alleles
|
|
A
|
316(77)/246(74)
|
1
|
G
|
324(79)/257(77)
|
1
|
|
G
|
92(23)/86(26)
|
1.01(0.71-1.45)
|
0.92
|
A
|
84(21)/75(23)
|
1.08(0.74-1.58)
|
0.65
|
|
p HWE**
|
0.72
|
p HWE**
|
0.26
|
- a. Odds ratio adjusted by age and HPV genotype.
- ** Hardy-Weinberg Equilibrium in controls (NCL).
- *p Value < = 0.01 adjusted by Bonferroni.
