Table 4 Clinical variables in hr HPV16+ patients and regression versus non-regression
Variable | Number n=54 (%) | Regression n=8 (%) | Non-regression n=46 (%) | p-value |
|---|---|---|---|---|
Age | ||||
(median, min-max, years) | 31 (25-41) | 31 (25-41) | 31 (25-41) | 0.9 |
≤30 | 20 (37) | 1 (5) | 19 (95) | 0.1 |
>30 | 34 (63) | 7 (20) | 27 (80) | |
Interval biopsy-cone | ||||
(median, min-max, days) | 113 (84-171) | 107 (84-154) | 113 (84-171) | 0.1 |
≤115 | 38 (70) | 6 (16) | 32 (84) | 0.7 |
>115 | 16 (30) | 2 (12) | 14 (88) | |
CIN diagnosis | ||||
CIN2 | 7 (13) | 2 (29) | 5 (71) | 0.3 |
CIN3 | 47 (87) | 6 (13) | 41 (87) | |
HPV genotype | ||||
Single | 32 (59) | 7 (22) | 25 (78) | 0.08 |
Multiple | 22 (41) | 1 (5) | 21 (95) | |
Smoking | ||||
Yes | 25 (46) | 5 (20) | 20 (80) | 0.3 |
No | 29 (54) | 3 (10) | 26 (90) | |
Number of sexual partners | ||||
1-9 | 16 (30) | 1 (6) | 15 (94) | 0.3 |
>10 | 38 (70) | 7 (18) | 31 (82) | |
Parity | ||||
Yes | 36 (67) | 6 (17) | 30 (83) | 0.6 |
No | 18 (33) | 2 (11) | 16 (89) | |
Age of first sexual intercourse | ||||
≤15 | 15 (28) | 2 (13) | 13 (87) | 0.8 |
>15 | 39 (72) | 6 (15) | 33 (85) | |
Sexual activity span | ||||
≤13 | 21 (39) | 1 (5) | 20 (95) | 0.1 |
>13 | 33 (61) | 7 (21) | 26 (79) | |
Condom use | ||||
Yes | 6 (11) | 1 (16) | 5 (83) | 0.9 |
No | 48 (89) | 7 (15) | 41 (85) | |