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Table 3 Clinical variables in hr HPV16- patients and regression versus non-regression

From: Consistent condom use increases spontaneous regression in high-risk non-HPV16 but not in HPV16 CIN2-3 lesions, a prospective population-based cohort study

Variable Number n=91 (%) Regression n=18 (%) Non-regression n=73 (%) p-value
Age
(median, min.-max., years) 30 (25-41) 29 (25-41) 30 (25-41) 0.8
≤30 46 (50) 10 (22) 36 (78) 0.6
>30 45 (50) 8 (18) 37 (82)  
Interval biopsy-cone
(median, min.-max., days) 113 (84-171) 108 (84-127) 113 (84-171) 0.1
≤115 63 (69) 14 (22) 49 (78) 0.4
>115 28 (31) 4 (14) 24 (86)  
CIN diagnosis
CIN2 19 (21) 5 (26) 14 (74) 0.4
CIN3 72 (79) 13 (18) 59 (82)  
HPV genotype
Single 59 (65) 13 (22) 46 (78) 0.5
Multiple 32 (35) 5 (16) 27 (84)  
Smoking
Yes 23 (25) 2 (9) 21 (91) 0.1
No 68 (75) 16 (24) 52 (76)  
Number of sexual partners
1-9 51 (56) 11 (22) 40 (78) 0.6
>10 40 (44) 7 (18) 33 (82)  
Parity
Yes 56 (62) 10 (18) 46 (82) 0.6
No 35 (39) 8 (23) 27 (77)  
Age of first sexual intercourse
≤15 23 (25) 1 (4) 22 (96) 0.03
>15 68 (75) 17 (25) 51 (75)  
Sexual activity span
≤13 43 (47) 11 (26) 32 (74) 0.2
>13 48 (53) 7 (15) 41 (85)  
Condom use
Yes 11 (12) 8 (73) 3 (27) <0.0001
No 80 (88) 10 (13) 70 (87)  
  1. 1min.-max.: minimum, maximum.