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Table 3 Clinical variables in hr HPV16- patients and regression versus non-regression
| Variable | Number n=91 (%) | Regression n=18 (%) | Non-regression n=73 (%) | p-value |
|---|---|---|---|---|
| Age | ||||
| (median, min.-max., years) | 30 (25-41) | 29 (25-41) | 30 (25-41) | 0.8 |
| ≤30 | 46 (50) | 10 (22) | 36 (78) | 0.6 |
| >30 | 45 (50) | 8 (18) | 37 (82) | |
| Interval biopsy-cone | ||||
| (median, min.-max., days) | 113 (84-171) | 108 (84-127) | 113 (84-171) | 0.1 |
| ≤115 | 63 (69) | 14 (22) | 49 (78) | 0.4 |
| >115 | 28 (31) | 4 (14) | 24 (86) | |
| CIN diagnosis | ||||
| CIN2 | 19 (21) | 5 (26) | 14 (74) | 0.4 |
| CIN3 | 72 (79) | 13 (18) | 59 (82) | |
| HPV genotype | ||||
| Single | 59 (65) | 13 (22) | 46 (78) | 0.5 |
| Multiple | 32 (35) | 5 (16) | 27 (84) | |
| Smoking | ||||
| Yes | 23 (25) | 2 (9) | 21 (91) | 0.1 |
| No | 68 (75) | 16 (24) | 52 (76) | |
| Number of sexual partners | ||||
| 1-9 | 51 (56) | 11 (22) | 40 (78) | 0.6 |
| >10 | 40 (44) | 7 (18) | 33 (82) | |
| Parity | ||||
| Yes | 56 (62) | 10 (18) | 46 (82) | 0.6 |
| No | 35 (39) | 8 (23) | 27 (77) | |
| Age of first sexual intercourse | ||||
| ≤15 | 23 (25) | 1 (4) | 22 (96) | 0.03 |
| >15 | 68 (75) | 17 (25) | 51 (75) | |
| Sexual activity span | ||||
| ≤13 | 43 (47) | 11 (26) | 32 (74) | 0.2 |
| >13 | 48 (53) | 7 (15) | 41 (85) | |
| Condom use | ||||
| Yes | 11 (12) | 8 (73) | 3 (27) | <0.0001 |
| No | 80 (88) | 10 (13) | 70 (87) | |
