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Table 3 Clinical variables in hr HPV16- patients and regression versus non-regression

From: Consistent condom use increases spontaneous regression in high-risk non-HPV16 but not in HPV16 CIN2-3 lesions, a prospective population-based cohort study

Variable

Number n=91 (%)

Regression n=18 (%)

Non-regression n=73 (%)

p-value

Age

(median, min.-max., years)

30 (25-41)

29 (25-41)

30 (25-41)

0.8

≤30

46 (50)

10 (22)

36 (78)

0.6

>30

45 (50)

8 (18)

37 (82)

 

Interval biopsy-cone

(median, min.-max., days)

113 (84-171)

108 (84-127)

113 (84-171)

0.1

≤115

63 (69)

14 (22)

49 (78)

0.4

>115

28 (31)

4 (14)

24 (86)

 

CIN diagnosis

CIN2

19 (21)

5 (26)

14 (74)

0.4

CIN3

72 (79)

13 (18)

59 (82)

 

HPV genotype

Single

59 (65)

13 (22)

46 (78)

0.5

Multiple

32 (35)

5 (16)

27 (84)

 

Smoking

Yes

23 (25)

2 (9)

21 (91)

0.1

No

68 (75)

16 (24)

52 (76)

 

Number of sexual partners

1-9

51 (56)

11 (22)

40 (78)

0.6

>10

40 (44)

7 (18)

33 (82)

 

Parity

Yes

56 (62)

10 (18)

46 (82)

0.6

No

35 (39)

8 (23)

27 (77)

 

Age of first sexual intercourse

≤15

23 (25)

1 (4)

22 (96)

0.03

>15

68 (75)

17 (25)

51 (75)

 

Sexual activity span

≤13

43 (47)

11 (26)

32 (74)

0.2

>13

48 (53)

7 (15)

41 (85)

 

Condom use

Yes

11 (12)

8 (73)

3 (27)

<0.0001

No

80 (88)

10 (13)

70 (87)

 
  1. 1min.-max.: minimum, maximum.