Table 2 Clinical variables in hr HPV16 + versus hr HPV16- patients
Variables | Number n=145 (%) | HPV16+ n=54 (%) | HPV16- n=91 (%) | p-value |
|---|---|---|---|---|
Regression | 26 (18) | 8 (15) | 18 (20) | 0.5 |
Non-regression | 119 (82) | 46 (85) | 73 (80) | |
Age | ||||
(median, min.-max., years) | 31 (25-41) | 32 (25-41) | 30 (25-41) | 1.0 |
≤30 | 66 (45) | 20 (37) | 46 (51) | 0.1 |
>30 | 79 (55) | 34 (63) | 45 (49) | |
Interval biopsy-cone | ||||
(median, min.-max., days) | 113 (84-171) | 107(84-154) | 113 (84-171) | 0.6 |
≤115 | 101 (70) | 38 (70) | 63 (69) | 0.9 |
>115 | 44 (30) | 16 (30) | 28 (31) | |
CIN diagnosis | ||||
CIN2 | 26 (18) | 7 (13) | 19 (21) | 0.2 |
CIN3 | 119 (82) | 47 (87) | 72 (79) | |
HPV genotype | ||||
Single | 91 (63) | 32 (60) | 59 (65) | 0.5 |
Multiple | 54 (37) | 22 (40) | 32 (35) | |
Smoking | ||||
Yes | 48 (33) | 25 (46) | 23 (25) | 0.009 |
No | 97 (67) | 29 (54) | 68 (75) | |
Number of sexual partners | ||||
1-9 | 67 (46) | 16 (30) | 51 (56) | 0.002 |
>10 | 78 (54) | 38 (70) | 40 (44) | |
Parity | ||||
Yes | 92 (63) | 36 (67) | 56 (62) | 0.5 |
No | 53 (37) | 18 (33) | 35 (38) | |
Age of first sexual intercourse | ||||
≤15 | 38 (26) | 15 (28) | 23 (25) | 0.7 |
>15 | 107 (74) | 39 (72) | 68 (75) | |
Sexual activity span | ||||
≤13 | 64 (44) | 21 (39) | 43 (47) | 0.3 |
>13 | 81 (56) | 33 (61) | 48 (53) | |
Condom use | ||||
Yes | 17 (12) | 6 (11) | 11 (12) | 0.9 |
No | 128 (88) | 48 (89) | 80 (88) | |