HPV type distribution in invasive cervical cancers in Italy: pooled analysis of three large studies

Table 3 HPV types 16/18 and HPV types 16/18/45 by histotype, study and age

		*<=24*	*25-34*	*35-44*	*45-54*	*55-64*	*65+*	*All ages*
Histological type
Squamous cell carcinoma	16/18 (n)	1	40	108	85	61	69	364
	%	100,0	93,0	76,1	72,6	72,6	75,0	76,0
	16/18/45 (n)	1	41	118	94	64	72	390
	%	100	95,3	83,1	80,3	76,2	78,3	81,4
	Any type (n)	1	43	142	117	84	92	479
Adeno- and Adenosquamous cell carcinoma	16/18 (n)	0	5	15	5	10	8	43
	%	0	100	93,8	55,6	83,3	61,5	76,8
	16/18/45 (n)	1	5	15	6	11	11	49
	%	100	100	93,8	66,7	91,7	84,6	87,5
	Any type (n)	1	5	16	9	12	13	56
Study
Milan Study	16/18 (n)	0	25	65	44	38	15	187
	%	-	89,3	75,6	71,0	73,1	71,4	75,1
	16/18/45 (n)	0	26	70	49	38	16	199
	%	-	92,9	81,4	79,0	73,1	76,2	79,9
	Any type (n)	0	28	86	62	52	21	249
Rome Study	16/18 (n)	1	9	25	14	16	15	80
	%	100,0	100,0	69,4	60,9	84,2	62,5	71,4
	16/18/45 (n)	1	9	28	17	16	15	86
	%	100,0	100,0	77,8	73,9	84,2	62,5	76,8
	Any type (n)	1	9	36	23	19	24	112
Central and Southern Italy Study	16/18 (n)	0	11	33	32	17	47	140
	%	0,0	100,0	91,7	78,0	68,0	78,3	80,5
	16/18/45 (n)	1	11	35	34	21	52	154
	%	100,0	100,0	97,2	82,9	84,0	86,7	88,5
	Any type (n)	1	11	36	41	25	60	174
Total	16/18 (n)	2	46	124	91	71	78	412
	%	66,7	93,9	78,0	71,7	74,0	73,6	76,3
	16/18/45 (n)	3	47	134	101	75	84	444
	%	100	95,9	84,3	79,5	78,1	79,2	82,2
	Any type (n)	3	49	159	127	96	106	540

*including five other minor histotypes; three cases with HPV type 18 and two cases with HPV type 16; one case in each age class except 55–64 years old.

ISSN: 1750-9378