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Table 3 Toxicological and Biochemical Biomarkers for Control, MNU, BCG and P-MAPA groups

From: Effects of P-MAPA Immunomodulator on Toll-Like Receptors and p53: Potential Therapeutic Strategies for Infectious Diseases and Cancer

Parameters Control MNU BCG P-MAPA
(n = 10) (n = 10) (n = 10) (n = 10)
ALT (U/L) 49.23 ± 1.61 46.03 ± 0.63 46.30 ± 3.60 51.61 ± 7.07
AST (U/L) 189.72 ± 28.74 133.05 ± 2.29 201.61 ± 23.84 208.38 ± 31.34
Alkaline Phosfatase (U/L) 42.97 ± 0.87a 128.11 ± 8.21 38.88 ± 3.51a 40.56 ± 3.93a
Urea (mg/dL) 55.45 ± 3.90a 163.09 ± 14.14 60.52 ± 5.90a 57.32 ± 7.16a
Creatinine (mg/dL) 1.18 ± 0.26a 10.33 ± 0.10 1.22 ± 0.25a 1.94 ± 1.24a
  1. Data expressed as mean ± SEM, p < 0.05; Letter a: significantly different from MNU group. MNU = n-methyl-n-nitrosourea; BCG = Bacillus Calmette-Guerin.