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Table 1 Weinberger classification (2006)

From: The role of human papillomavirus in the pathogenesis of head & neck squamous cell carcinoma: an overview

Weinberger classification (2006)*

HPV status; p16 expression

Median HPV DNA viral load (copies HPV 16/human genome)

Class I, HPV-; p16 low

0.0 copies - Class I

Class II, HPV+; p16 low

3.6 copies - Class II

Class III, HPV+; p16 high

46.0 copies - Class III

Class IV, HPV-; p16 +

 
  1. For further detail see the text
  2. *according to the contents reported in: Weinberger PM, et al.: Molecular classification identifies a subset of human papillomavirus--associated oropharyngeal cancers with favorable prognosis. J Clin Oncol 2006, 24(5):736-47 [67]