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Table 5 Concordance values by techniques and HPV type

From: Performance of the digene LQ, RH and PS HPVs genotyping systems on clinical samples and comparison with HC2 and PCR-based Linear Array

GENOTYPE

LA vs. LQ/RH

LQ

RH

LA vs. PS

PS

 

(n)

(n)

kappa (95% CI)

McNemar's

p-value

(n)

kappa (95% CI)

McNemar's

p-value

(n)

(n)

kappa (95% CI)

McNemar's

p-value

HPV 16

90

93

0.898 (0.845 - 0.952)

0.581

91

0.898 (0.844 - 0.952)

1.000

90

73

0.825 (0.753 - 0.896)

0.000

HPV 16 SI

36

51

0.720 (0.608 - 0.832)

0.001

60

0.658 (0.543 - 0.772)

0.000

81

69

0.806 (0.728 - 0.883)

0.017

HPV 16 MI

54

42

0.581 (0.455 - 0.707)

0.058

31

0.473 (0.335 - 0.611)

0.000

9

4

0.452 (0.114 - 0.790)

0.125

HPV 18

20

25

0.736 (0.588 - 0.885)

0.227

22

0.795 (0.658 - 0.933)

0.727

20

14

0.751 (0.586 - 0.916)

0.070

HPV 18 SI

5

8

0.607 (0.292 - 0.923)

0.375

9

0.562 (0.249 - 0.876)

0.219

13

12

0.708 (0.502 - 0.914)

1.000

HPV 18 MI

15

17

0.538 (0.324 - 0.752)

0.791

13

0.626 (0.412 - .840)

0.754

7

2

0.439 (0.035 - 0.842)

0.063

HPV 45

9

11

0.897 (0.754 - 1.000)

0.500

9

0.886 (0.728 - 1.000)

1.000

9

8

0.818 (0.617 - 1.000)

1.000

HPV45 SI

5

6

0.907 (0.727 - 1.000)

1.000

5

1.00 (1.000 - 1.000)

1.000

7

6

0.921 (0.768 - 1.000)

1.000

HPV 45 MI

4

5

0.662 (0.302 - 1.000)

1.000

4

0.747 (0.408 - 1.000)

1.000

2

2

0.497 (0.000 - 1.000)

1.000

HPV 31

41

39

0.885 (0.806 - 0.963)

0.727

36

0.837 (0.742 - 0.931)

0.227

    

HPV 58

36

26

0.821 (0.714 - 0.928)

0.020

23

0.757 (0.632 - 0.882)

0.000

    

HPV 51

34

28

0.785 (0.667 - 0.902)

0.146

21

0.702 (0.561 - 0.843)

0.001

    

HPV 52

33

21

0.474 (0.304 - 0.645)

0.029

21

0.515 (0.347 - 0.683)

0.023

    

HPV 66

28

27

0.820 (0.706 - 0.935)

1.000

23

0.808 (0.686 - 0.930)

0.180

    

HPV 53

28

11

0.486 (0.293 - 0.679)

0.000

8

0.421 (0.221 - 0.621

0.000

    

HPV 39

25

17

0.796 (0.659 - 0.933)

0.008

17

0.745 (0.594 - 0.896)

0.021

    

HPV 33

21

22

0.825 (0.698 - 0.952)

1.000

20

0.869 (0.756 - 0.982)

1.000

    

HPV 56

21

29

0.739 (0.599 - 0.880)

0.039

28

0.756 (0.618 - 0.894)

0.065

    

HPV 59

20

10

0.651 (0.452 - 0.851)

0.002

10

0.651 (0.452 - 0.851)

0.002

    

HPV 35

12

11

0.955 (0.866 - 1.000)

1.000

9

0.852 (0.688 - 1.000)

0.250

    

HPV 68

10

9

0.620 (0.360 - 0.879)

1.000

10

0.586 (0.326 - 0.847)

1.000

    

HPV 73

9

4

0.608 (0.295 - 0.922)

0.063

2

0.357 (0.000 - 0.717)

0.016

    

HPV 82

4

6

0.594 (0.231 - 0.956)

0.625

6

0.797 (0.522 - 1.000)

0.500

    

HPV 26

2

2

0.497 (0.000 - 1.000)

1.000

1

0.665 (0.048 - 1.000)

1.000

    
  1. "n": Number of cases HPV type-specific positive; "CI": Confidence interval.
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Infectious Agents and Cancer

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