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Table 1 Clinicopathologic Features of 149 Cervical Cancer Cases

From: HPV16 variant lineage, clinical stage, and survival in women with invasive cervical cancer

TRAIT

CATEGORY

EUROPEAN (%1)

n = 127

NON EUROPEAN (%1)

n = 22

TOTAL (%2)

P-VALUE3

n = 149

 

Squamous Carcinoma

119 (87.5)

17 (12.5)

136 (91.3)

 

CELL TYPE

Adenocarcinoma

5 (55.6)

4 (44.4)

9 (6.0)

0.03

 

Adenosquamous Ca

3 (75.0)

1 (25.0)

4 (2.7)

 

AGE GROUP

20-40

46 (78.0)

13 (22.0)

59 (39.6)

 

(YEARS)

41-50

46 (92.0)

4 (8.0)

50 (33.6)

0.13

 

51-72

35 (87.5)

5 (12.5)

40 (26.8)

 
 

White

102 (88.7)

13 (11.3)

115 (77.7)

 

RACE

Black

4 (80.0)

1 (20.0)

5 (3.4)

0.11

 

Hispanic

7 (63.6)

4 (36.4)

11 (7.4)

 
 

Native American

10 (71.4)

4 (28.6)

14 (9.5)

 
 

Asian

2 (100)

0

2 (1.4)

 
 

Other

1 (100)

0

1 (0.7)

 
 

Unknown

1 -

-

1 -

 
 

1A

14 (87.5)

2 (12.5)

16 (11.1)

 

STAGE (FIGO)

1B1

42 (75.0)

14 (25.0)

56 (38.9)

0.16

 

1B2

16 (88.9)

2 (11.1)

18 (12.5)

 
 

2

22 (91.7)

2 (8.3)

24 (16.7)

 
 

3

18 (94.7)

1 (5.3)

19 (13.2)

 
 

4

11 (8.9)

0

11 (7.6)

 
 

Recurrent/Unstaged

4 -

1 -

5 -

 
 

0

6 (85.7)

1 (14.3)

7 (4.9)

 

GRAVIDITY

1-3

73 (82.0)

16 (18.0)

89 (61.8)

0.13

 

>3

45 (93.8)

3 (6.3)

48 (33.3)

 
 

ND4

3 -

2 -

5 -

 

PARAMETRIA5

Negative

53 (77.9)

15 (22.1)

68 (60.7)

0.12

 

Positive

40 (90.9)

4 (9.1)

44 (39.3)

 
 

ND

34 -

3 -

37 -

 

Table 1 (cont'd)

     
 

<1

16 (84.2)

3 (15.8)

19 (14.6)

 

TUMOR SIZE5 (cm)

1-4

42 (76.4)

13 (23.6)

55 (42.3)

0.1

 

>4

51 (91.1)

5 (8.9)

56 (43.1)

 
 

ND

18 -

1 -

19 -

 
 

< 3

15 (93.8)

1 (6.3)

16 (19.3)

 

INVASION DEPTH6

3.1 - 5.0

10 (83.3)

2 (16.7)

12 (14.5)

0.21

(mm)

>5

40 (72.7)

15 (27.3)

55 (66.3)

 
 

ND

62 -

4 -

66 -

 
 

Positive

40 (74.1)

14 (25.9)

54 (62.1)

 

VSI6

Negative

29 (87.9)

4 (12.1)

33 (37.9)

0.17

 

ND

58 -

4 -

62 -

 

RESECTION

Positive

11 (91.7)

1 (8.3)

12 (14.6)

 

MARGINS6

Negative

53 (75.7)

17 (24.3)

70 (85.4)

0.29

 

ND

63 -

4 -

67 -

 

LYMPH NODES7

Negative

48 (85.7)

8 (14.3)

56 (50.4)

 
 

Positive

44 (80.0)

11 (20.0)

55 (49.6)

0.46

 

ND

35 -

3 -

38 -

 
 

NED

86 (80.4)

21 (19.6)

107 (71.8)

 

STATUS8

DOD

41 (97.6)

1 (2.4)

42 (28.2)

0.008

  1. 1: Percentage calculated across.
  2. 2: Percentage calculated down.
  3. 3: Fisher's Exact Test
  4. 4: ND: No data available
  5. 5: Parametrial assessment and tumor size were determined by pathologic analysis of a radical hysterectomy or as part of a clinical staging procedure.
  6. 6: Depth of invasion, margin status and status of vascular space invasion were available only for women with early stage tumors who had a conization or hysterectomy.
  7. 7: Lymph node dissections were routinely performed as part of radical hysterectomy. It is not standard for higher stage women although cervical biopsy with lymph node dissection was performed for some higher stage women.
  8. 8: Status: NED = No evidence of cervical cancer at last follow-up; DOD = Dead of cervical cancer
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Infectious Agents and Cancer

ISSN: 1750-9378

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