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Table 1 Clinicopathologic Features of 149 Cervical Cancer Cases

From: HPV16 variant lineage, clinical stage, and survival in women with invasive cervical cancer

TRAIT CATEGORY EUROPEAN (%1)
n = 127
NON EUROPEAN (%1)
n = 22
TOTAL (%2) P-VALUE3
n = 149
  Squamous Carcinoma 119 (87.5) 17 (12.5) 136 (91.3)  
CELL TYPE Adenocarcinoma 5 (55.6) 4 (44.4) 9 (6.0) 0.03
  Adenosquamous Ca 3 (75.0) 1 (25.0) 4 (2.7)  
AGE GROUP 20-40 46 (78.0) 13 (22.0) 59 (39.6)  
(YEARS) 41-50 46 (92.0) 4 (8.0) 50 (33.6) 0.13
  51-72 35 (87.5) 5 (12.5) 40 (26.8)  
  White 102 (88.7) 13 (11.3) 115 (77.7)  
RACE Black 4 (80.0) 1 (20.0) 5 (3.4) 0.11
  Hispanic 7 (63.6) 4 (36.4) 11 (7.4)  
  Native American 10 (71.4) 4 (28.6) 14 (9.5)  
  Asian 2 (100) 0 2 (1.4)  
  Other 1 (100) 0 1 (0.7)  
  Unknown 1 - - 1 -  
  1A 14 (87.5) 2 (12.5) 16 (11.1)  
STAGE (FIGO) 1B1 42 (75.0) 14 (25.0) 56 (38.9) 0.16
  1B2 16 (88.9) 2 (11.1) 18 (12.5)  
  2 22 (91.7) 2 (8.3) 24 (16.7)  
  3 18 (94.7) 1 (5.3) 19 (13.2)  
  4 11 (8.9) 0 11 (7.6)  
  Recurrent/Unstaged 4 - 1 - 5 -  
  0 6 (85.7) 1 (14.3) 7 (4.9)  
GRAVIDITY 1-3 73 (82.0) 16 (18.0) 89 (61.8) 0.13
  >3 45 (93.8) 3 (6.3) 48 (33.3)  
  ND4 3 - 2 - 5 -  
PARAMETRIA5 Negative 53 (77.9) 15 (22.1) 68 (60.7) 0.12
  Positive 40 (90.9) 4 (9.1) 44 (39.3)  
  ND 34 - 3 - 37 -  
Table 1 (cont'd)      
  <1 16 (84.2) 3 (15.8) 19 (14.6)  
TUMOR SIZE5 (cm) 1-4 42 (76.4) 13 (23.6) 55 (42.3) 0.1
  >4 51 (91.1) 5 (8.9) 56 (43.1)  
  ND 18 - 1 - 19 -  
  < 3 15 (93.8) 1 (6.3) 16 (19.3)  
INVASION DEPTH6 3.1 - 5.0 10 (83.3) 2 (16.7) 12 (14.5) 0.21
(mm) >5 40 (72.7) 15 (27.3) 55 (66.3)  
  ND 62 - 4 - 66 -  
  Positive 40 (74.1) 14 (25.9) 54 (62.1)  
VSI6 Negative 29 (87.9) 4 (12.1) 33 (37.9) 0.17
  ND 58 - 4 - 62 -  
RESECTION Positive 11 (91.7) 1 (8.3) 12 (14.6)  
MARGINS6 Negative 53 (75.7) 17 (24.3) 70 (85.4) 0.29
  ND 63 - 4 - 67 -  
LYMPH NODES7 Negative 48 (85.7) 8 (14.3) 56 (50.4)  
  Positive 44 (80.0) 11 (20.0) 55 (49.6) 0.46
  ND 35 - 3 - 38 -  
  NED 86 (80.4) 21 (19.6) 107 (71.8)  
STATUS8 DOD 41 (97.6) 1 (2.4) 42 (28.2) 0.008
  1. 1: Percentage calculated across.
  2. 2: Percentage calculated down.
  3. 3: Fisher's Exact Test
  4. 4: ND: No data available
  5. 5: Parametrial assessment and tumor size were determined by pathologic analysis of a radical hysterectomy or as part of a clinical staging procedure.
  6. 6: Depth of invasion, margin status and status of vascular space invasion were available only for women with early stage tumors who had a conization or hysterectomy.
  7. 7: Lymph node dissections were routinely performed as part of radical hysterectomy. It is not standard for higher stage women although cervical biopsy with lymph node dissection was performed for some higher stage women.
  8. 8: Status: NED = No evidence of cervical cancer at last follow-up; DOD = Dead of cervical cancer