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Figure 3 | Infectious Agents and Cancer

Figure 3

From: Hypoxia inducible factor-1 alpha expression is increased in infected positive HPV16 DNA oral squamous cell carcinoma and positively associated with HPV16 E7 oncoprotein

Figure 3

Labeling indexes immunoreactivity for HIF-1α in pT1-T2 and pT3-T4 oral squamous cell carcinomas. pT1-T2 tumors showed a significant increase in mean values of the HIF-1α labeling indexes in infected positive HPV16 DNA tumors than non-infected tumors (48.31 ± 17.14 vs. 24.59 ± 15.58; p < .001); pT3-T4 tumors did not showed significant differences in mean values of the HIF-1α labeling indexes between infected positive HPV16 DNA tumors and non-infected tumors (82.94 ± 9.77 vs. 73.96 ± 8.64; p = .07). Differences were analyzed by the Mann-Whitney test; statistical results were considered significant for p values < .05.

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Infectious Agents and Cancer

ISSN: 1750-9378

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