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Table 1 Association between AIDS-defining cancers with HIV in children and adults in studies conducted in sub-Saharan Africa

From: HIV and cancer in Africa: mutual collaboration between HIV and cancer programs may provide timely research and public health data

Cancer Country Subjects OR (95%CI) Reference
Kaposi sarcoma Uganda Children 94.9 (28.5-315) Newton et al., 2001[47]
  Malawi Children 93.5 (26.9-324) Newton et al., 1995[67]
  Uganda Adults 6.4 (4.8-8.4) Mbulaiteye et al., 2006 ± [46]
  Rwanda Adults 35 (8.2-207) Newton et al., 1995[72]
  South Africa Adults 22 (12.5-39) Sitas et al., 2000[73]
  South Africa Adults 47.1 (31.9-69.8) Stein et al., 2000[74]
Non-Hodgkin lymphoma     
Burkitt lymphoma Uganda Children 7.5 (2.8-20.1) Newton et al., 2001[47]
  Uganda Children 2.2 (0.9-5.1) Parkin et al., 2000[51]
  Malawi Children 12.4 (1.3-116) Mutalima et al., 2008[68]
  Malawi Children 2.2 (0.8-6.4) Mutalima et al., 2010[67]
  South Africa Children 46.2 (16.4-130) Stefan et al., 2011[69]
Non-Burkitt NHL Malawi Children 4.4 (1.1-17.9) Mutalima et al., 2010[67]
  South Africa Children 5.0 (0.9-27.0) Stefan et al., 2011[69]
  Uganda Adults 6.2 (1.9-20) Newton et al., 2001[47]
  Uganda Adults 6.7 (1.8-17) Mbulaiteye et al., 2006 ± [46]
  South Africa Adults 5.0 (2.7-9.5) Sitas et al., 2000[73]
  South Africa Adults 5.9 (4.3-8.1) Stein et al., 2000[74]
Cervical cancer Uganda Adults 1.6 (0.7-3.6) Newton et al., 2001[47]
  Uganda Adults 2.4 (1.1-4.4) Mbulaiteye et al., 2006 ± [46]
  South Africa Adults 1.6 (1.1-2.3) Sitas et al., 2000[73]
  South Africa Adults 1.6 (1.3-2.0) Stein et al., 2008[74]
  1. ± Results based on record-linkage study; estimates represent standardized incidence ratios comparing risk of cancer in persons with HIV to the general population where cancers arose. OR, odds ratio; 95%CI, 95% confidence interval.