Figure 1From: Retroviruses and retroelements in diseases and in gene therapy: 15 years laterScheme of retrovirus integration (modified from Goff 1992)[30]. Note that linear viral DNA integrates in antiparallel host cell DNA strands. Ends of viral DNA comprising critical part of long terminal repeats are boxed. N denotes nucleotide- complementary nucleotide. A full description of integration steps is given in the text.Back to article page