A population-based cross-sectional study of age-specific risk factors for high risk human papillomavirus prevalence in rural Nigeria

Clarke, Megan A; Gage, Julia C; Ajenifuja, Kayode O; Wentzensen, Nicolas A; Adepiti, Akinfolarin C; Wacholder, Sholom; Burk, Robert D; Schiffman, Mark

doi:10.1186/1750-9378-6-12

Table 1 Clinical questionnaire responses and potential risk factors for high risk human papillomavirus positivity

From: A population-based cross-sectional study of age-specific risk factors for high risk human papillomavirus prevalence in rural Nigeria

		Total		Positive for one or more HR-HPV genotypes
	Categories	n	(%)	n	(%)	OR	95% CI	p-value^c
Age (yrs) (mean = 45.2 ± 17, median = 45)	15 - 29	300	21.1	49	18.9	1.3	0.9 - 2.0
Mean = 45.2, median = 45	30 - 45	452	31.8	55	12.8	0.8	0.6 - 1.2
	46 - 55	238	16.8	29	12.7	0.8	0.5 - 1.3
	56+	430	30.3	55	15.1	1.0	Ref	0.14
Age of Menarche (yrs)	10 - 14	224	17.6	33	16.1	1.0	0.6 - 1.8
Mean = 16.1, median = 15	15 - 19	891	70.0	119	14.6	0.9	0.6 - 1.5
	20 - 25	158	12.4	22	15.9	1.0	Ref	0.83
Age at Sexual Debut (yrs)	10-14	47	3.5	12	25.5	2.4	1.1 - 5.3
Mean = 20.0, median = 20	15-24	1,059	79.7	148	14.8	1.2	0.8 - 2.0
	25+	223	16.8	23	12.2	1.0	Ref	0.10
Age at First Pregnancy (yrs)	12-19	178	14.4	27	16.2	1.4	0.9 - 2.4
Mean = 23.1, median = 23	20-24	523	42.4	84	17.1	1.5	1.1 - 2.2
	25+	534	43.2	56	11.8	1.0	Ref	0.05
Lifetime No. of Pregnancies	1 - 4	370	28.9	54	15.7	1.1	0.7 - 1.8
Mean = 6.5, median = 6	5 - 9	660	51.5	88	14.5	1.0	0.7 - 1.6
	10+	251	19.6	32	14.2	1.0	Ref	0.86
No. of Sex Partners (past 2 yrs)	2+	311	23.1	54	18.2	1.4	1.0 - 2.0
Mean = 1.3, median = 1	1	1,034	76.9	131	13.9	1.0	Ref	0.07
Current Birth Control Use	Yes	185	13.9	37	20.3	1.6	1.1 - 2.4
	No	1,147	86.1	144	13.9	1.0	Ref	0.03
Current Marital Status ^a	Not in Union	450	33.5	66	16.4	1.2	0.9 - 1.7
	In Union	895	66.5	117	13.9	1.0	Ref	0.25
In Household with Co-wives	Yes	553	40.1	70	13.5	0.8	0.6 - 1.1	0.24
	No	825	59.9	116	15.9	1.0	Ref
No. Other Wives	1	185	37.2	29	16.4	1.3	0.7 - 2.4
Mean = 2.1, median = 2	2	168	33.8	14	9.0	0.6	0.3 - 1.4
	3+	144	29.0	18	13.3	1.0	Ref	0.13
Rank Among Other Wives	1^st	222	45.0	26	12.4	1.3	0.6 - 2.9
Mean = 1.8, median = 2	2^nd	172	34.9	25	15.5	1.7	0.8 - 3.8
	3^rd	99	20.1	9	9.8	1.0	Ref	0.40
Age of Youngest Wife (yrs)	15 - 29	42	13.9	8	19.1	0.7	0.2 - 2.2
Mean = 39.4, median = 40	30 - 59	236	78.1	25	11.4	0.4	0.1 - 1.0
	60+	24	8.0	6	26.1	1.0	Ref	0.11
Tobacco Exposure ^b	Yes	121	15.2	20	17.5	1.3	0.8 - 2.3
	No	675	84.8	87	13.8	1.0	Ref	0.31
Number of Malaria Diagnoses (past 2 yrs)	3+	453	35.2	64	15.5	1.1	0.6 - 2.1
	2	371	28.9	45	13.4	0.9	0.5 - 1.8
Mean = 2.2, median = 2	1	355	27.6	43	13.7	0.9	0.5 - 1.8
	0	107	8.3	14	14.3	1.0	Ref	0.85

a - In Union includes a woman who is either married or living with a man;
b -A "yes" response includes 77 women whose husbands smoke and 44 women who currently use tobacco
c - p-trend for variables with more than two response categories.

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ISSN: 1750-9378

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