Figure 5

Nucleotide and amino acid sequence variation in OSSN and pterygia patients. Shown are representative samples of the most common HPV types detected by sequencing using GP5+/GP6+ primers of the L1 region. The table shows nucleotide variation and amino acid changes. The top 4 rows show the nucleotide position, the 5^th row shows the HPV reference nucleotide sequence, the 6^th row shows the variation in patient nucleotide sequence, and the 7^th row is the resulting variant amino acid sequence. In each HPV type, the variations were the same for each study case in the selected nucleotide sequence with some differences upstream and downstream in the different subjects, except case #15 which varied in a specific nucleotide in all HPV types, besides HPV-1.