Skip to main content

Table 1 General characteristics of 541 children with cancer diagnosed in Blantyre, Malawi

From: Impact of infection with human immunodeficiency virus-1 (HIV) on the risk of cancer among children in Malawi - preliminary findings

    

Cancer diagnosis

n (%)

    
 

Burkitt lymphoma

Wilms tumour

Kaposi sarcoma

Other lymphoma

Rhabdo-myosarcoma

Retino-blastoma

Other tumours

Non-malignant conditions

Total**

 

284 (52)

53 (10)

34 (6)

36 (7)

28 (5)

22 (4)

61 (11)

23 (4)

541 (100)

Sex:

         

   Female

112 (39)

23 (43)

13 (39)

13 (36)

11 (39)

14 (64)

26 (43)

9 (39)

221 (41)

   Male

172 (61)

30 (57)

20 (61)

23 (64)

17 (61)

8 (36)

35 (57)

14 (61)

319 (59)

Age at diagnosis*

         

   0 to 5 years old

57 (21)

37 (74)

12 (41)

5 (15)

14 (52)

20 (95)

21 (39)

10 (45)

176 (35)

   ≥ 5 years old

213 (79)

13 (26)

17 (59)

28 (85)

13 (48)

1 (5)

33 (61)

12 (55)

330 (65)

   Mean (se)

7.47 (0.18)

4.09 (0.34)

7.24 (0.75)

9.40 (0.68)

5.43 (0.73)

3.10 (0.36)

7.25 (0.61)

5.68 (1.04)

6.91 (0.16)

Residence

         

   Rural

199 (71)

37 (73)

15 (45)

25 (69)

19 (68)

13 (65)

42 (70)

14 (64)

364 (69)

   Urban

80 (29)

14 (27)

18 (55)

11 (31)

9 (32)

7 (35)

18 (30)

8 (36)

165 (31)

Method of diagnosis

         

   Clinical signs

38 (13)

8 (15)

18 (53)

7 (19)

8 (29)

7 (32)

8 (13)

7 (30)

101 (19)

   Clinical investigations

46 (16)

5 (9)

11 (32)

9 (25)

6 (21)

5 (23)

8 (13)

5 (22)

95 (18)

   Laboratory confirmed

197 (69)

37 (70)

5 (15)

20 (56)

13 (46)

10 (45)

43 (70)

11 (48)

336 (62)

   Not Recorded

3 (1)

3 (6)

0 (0)

0 (0)

1 (4)

0 (0)

2 (3)

0 (0)

9 (2)

HIV status ¥

         

   Positive

20 (7)

1 (2)

24 (77)

5 (14)

0 (0)

0 (0)

1 (2)

3 (14)

54 (10)

   Negative

263 (93)

51 (98)

7 (23)

31 (86)

28 (100)

16 (100)

57 (98)

18 (86)

471 (90)

  1. Non-Burkitt Non-Hodgkin lymphoma and unspecified lymphomas,Other tumours include: Neuroblastoma(17), Germ Cell tumours(16), Hepatic tumours(9), Bone tumours(5), Cranial tumours (4), Soft tissue sarcomas(4), Epithelial tumours (4), Renal carcinomas(1) and Other carcinomas (1), Non-malignant conditions include: Aplastic anaemia, Benign cystic teratoma, Benign mesenchymal tumour, Cellular mesoblastic nephroma, Chronic inflammation, Chronic osteomyelitis, Dental cyst, Dentrigenous cyst, Encephalitis, Haemangioma, Liver abscess, Melanotic neuroectodermal tumour of infancy, Pleomorphic adenoma, Ranula, Salivary gland tumour, unclassified soft tissue tumour, Teratoma, Torted ectopic spleen and Tuberculosis, *35 patients had missing age data, See methods section, ¥16 patients had missing HIV serology, **excludes 8 patients with leukaemia and 10 with Hodgkin lymphoma.