Figure 3

Experimental design. 1) Examine bacterial attachment to and invasion into cancer cells in the presence of the anticancer drug that induces the SOS response. 2) Use proteomic analysis to reveal the bacterial proteins that exhibit changes in expression. 3) Identify the genes encoding cancer adhesion and invasion. 4) Construct the mutants for the genes, clone and express these genes. And 5) examine the bacterial capture and invasion of cancer cells in contrast to non-cancer control.