Figure 4

Boxplot of seroreactivity expressed as normalized OD 450 values of NPC sera in IgA/EBNA-1 ELISA (A) and IgA/VCA-p18 ELISA (B) versus BARF1 amino acid conversion. The cutoff value was set on 0.3 [51]. The bar in the boxplot indicates the median value. Serology results did not relate to the presence of variant BARF1 (Mann-Whitney U test p = 0.802 and 0.382 respectively).