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Table 1 Lytic and latent KSHV antibody levels and Odds Ratios (OR's) for seropositivity by municipal region, HIV and syphilis status and education

From: Kaposi's Sarcoma Associated-Herpes Virus (KSHV) Seroprevalence in Pregnant Women in South Africa

   

Lytic K8.1

Latent Orf 73

 

Total (n)

Age Mean (± SD)

Total Positive (n) (% Positive)

Antibody level μg(SD range)

Adjusted OR (95%CI)

Total Positive (n)

Antibody level μg(SD range)*

Adjusted OR (95%CI)

All Subjects

1740

26.0(6.2)

568(32.6)

0.77(0.31 -1.38)

-

568(32.6)

0.40(0.11-0.76)

-

Municipality Region

        

Soweto

293

24.9(5.8)ab

76(25.9)

0.71(0.27-1.29)b

1

79(27.0)

0.37(0.09-0.73)

1

Ekurhuleni

567

26.5(6.3)a

204(36.0)

0.79(0.30 - 1.46)

1.7(1.2 - 2.3)*

195(34.4)

0.40(0.11-0.77)

1.5(1.0 - 2.1)

Emfuleni

330

25.9(6.3)

107(32.4)

0.75(0.32-1.32)

1.5(1.0 - 2.1)*

118(35.8)

0.40(0.13-0.74)

1.7(1.2 - 2.4)*

Tshwane

207

25.8(6.1)

53(25.6)

0.71(0.32 -1.21)a

1.1(0.7 - 1.7)

52(25.1)

0.36(0.10-0.68)

1.0(0.7 - 1.6)

West Rand

343

26.4 (6.1)b

128(37.3)

0.84(0.37-1.49)ab

1.6(1.1 - 2.3)*

124(36.2)

0.43(0.13-0.82)

1.5(1.0 - 2.2) *

P 4df

 

0.0063

 

0.0069

0.0233

 

0.0675

0.0185

Education Level

        

< 2 years

117

28.5 (7.9)a

46(39.3)

0.90(1.67-0.35)a

1

47(40.2)

0.45(0.12-0.90)

1

2 - 5 years

513

26.5 (6.8)b

193(37.6)

0.82(0.32-1.48)b

0.8 (0.5 - 1.2)

176(34.3)

0.40(0.11-0.85)

0.6(0.4 - 1.0)

6 - 12 years

119

26.4 (5.6)

35(29.4)

0.75(0.30-1.36)

0.4(0.3 - 0.8)*

37(31.1)

0.42(0.14-0.80)

0.5(0.3 - 0.9) *

Post Matric

959

25.4 (5.5)ab

286(29.8)

0.73(0.31-1.30)ab

0.6(0.4 - 0.8)*

300(31.3)

0.42(0.11-0.72)

0.6(0.4 - 0.9) *

P 3df

 

0.042

 

0.0019

0.002

 

0.0874

0.0426

HIV Infection

        

Negative

1338

26.2 (6.4)

345(25.8)

0.70(0.28-1.27)

1

341(25.5)

0.36(0.09-0.68)

1

Positive

402

25.3 (5.4)

223(55.5)

1.00(0.50-1.69)

3.7(2.9 - 4.7) *

227(56.5)

0.54(0.21-0.98)

3.8(3.0 - 4.8) *

P 1df

 

0.011

 

< 0.0001

< 0.0001

 

< 0.0001

< 0.0001

Syphilis Infection

        

Negative

1442

25.9 (6.2)

461(32.0)

0.77(0.31-1.38)

1

454(31.5)

0.39(0.10-0.75)

1

Positive

298

26.4 (5.8)

107(35.9)

0.79(0.34-1.38)

1.0 (0.7 - 1.3)

114(38.3)

0.43(0.15-0.81)

1.2 (0.9 - 1.6)

P 1df

 

0.24

 

0.55

0.8924

 

0.087

0.2395

  1. #μg(SD range) geometric mean and standard deviation range. Means with the same letter are significantly different (p, 0.05). * Statistically significant Odds Ratios.