Elevated anti-Zta IgG levels and EBV viral load are associated with site of tumor presentation in endemic Burkitt's lymphoma patients: a case control study

Table 1 The demographic and clinical characteristics of the study participants

Parameters	Controls (n = 25)	BL (n = 32)	P value^a	BL with abdominal (n = 16)	BL with jaw (n = 14)	P value^a
Mean age years [range]*	7.6[5.5-10]	7.5[5-11]	n.s.	9.2[6.3-11]	5.6[3.8-6.50]	0.0018
Gender n (% male)	16(64)	21(66)	n.s.	11(79)	9(56)	n.s
Parasitemia n (% positive)	17(68)	4(13)	< 0.0001	4(29)	0(0)	< 0.0001
LDH (U/l) [SEM] **	467 (19.1)	1378(165.1)	< 0.0001	1716(236.2)	994.6(231.3)	< 0.0001
EBV viral load (Log copies/ml)[SEM]	.996 (0.36)	3.552(0.26)	< 0.0001	3.32(0.308)	3.81(0.407)	0.0483

*Data are presented as medians (in brackets are the 25^th and 75^th percentiles). ^a Mann-Whitney test was used to determine differences in medians between controls and BL patients and between patients with jaw and abdominal tumors. n.s denotes non significant p values. Abbreviation: BL, Burkitt's Lymphoma; LDH, lactose dehydrogenase; SEM, standard error of mean. **n = 30 BL patients

ISSN: 1750-9378