Figure 2

Average nucleotide divergence of C2-V5 env gene versus standard sequences of different clades. The shown average divergence values have been obtained aligning the Italian sequences with standard sequences of individual clades, Groups and CRF02_AG. (A) The lowest average divergence value of the whole group of sequences is versus B standard sequences (arrow); (B) the sample PR06.07 shows the lowest average divergence value versus CRF02_AG standards (arrow); (C) the sample PR06.03 shows the lowest average divergence versus clade C standard sequences (arrow) (p < 0.01).