Skip to main content

Table 1 Individual microscopic findings

From: Immunization of mice with the nef gene from Human Immunodeficiency Virus type 1: Study of immunological memory and long-term toxicology

Group:Animal Lung Liver Spleen Lymph Node Kidney Ovaries
MVAx3:1 0 0 0 0 0 nd
MVAx3:2 Congestion 3 0 0 nd 0 0
MVAx3:3 0 0 0 nd 0 nd
MVAx3:4 0 0 0 0 0 0
MVAx3:5 0 MiFo inflammation 2 0 0 Unilateral Chro pyelonephritis 1 0
MVAx3:6 Lymphoid cell acc. 2 MiFo inflammation 1 0 0 0 0
MVAx3:7 Lymphoid cell acc. 2 0 0 0 0 0
MVAx3:8 0 Peri. inflammation 2 Incr. extramedullary hematopoiesis 2 nd 0 0
MVAx3:9 0 0 0 nd 0 Unilateral cyst
MVAx3:10 Lymphoid cell acc. 1 Peri. inflammation 1 Incr. extramedullary hematopoiesis 1 Hemosiderosis 1 0 0 nd
PBSx2+MVAx1:1 Lymphoid cell acc. 1 MiFo inflammation 1 0 nd 0 0
PBSx2+MVAx1:2 0 0 0 nd 0 nd
PBSx2+MVAx1:3 0 0 0 nd 0 0
PBSx2+MVAx1:4 0 0 0 0 0 0
PBSx3:1 0 MiFo inflammation 2 Lymphoid hyperplasia 1 0 0 0
PBSx3:2 Lymphoid cell acc. 1 0 0 nd 0 0
PBSx3:3 0 0 0 nd 0 0
PBSx3:4 0 0 0 nd 0 nd
PBSx3:5 0 0 0 0 0 0
PBSx3:6 0 0 0 0 0 0
  1. Abbreviations: acc = accumulation, MiFo = Microfocal, Incr = Increased, Peri = Periportal, Chro = Chronic, nd = not done
  2. Grading of changes: 0 = No changes, 1 = Minimal changes, 2 = Slight changes, 3 = moderate changes, 4 = Marked changes, 5 = Severe changes,