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Figure 4 | Infectious Agents and Cancer

Figure 4

From: Immunization of mice with the nef gene from Human Immunodeficiency Virus type 1: Study of immunological memory and long-term toxicology

Figure 4

Nef responses as measured by ELISpot. (A) IFN-γ and (B) IL-2 secretion by splenocytes stimulated with either a pool of overlapping peptides covering Nef or a pool of control peptides (Tick Borne Encephalitis virus, TBE). * indicates a significant difference (p < 0.05). Error bars show standard deviations of all animals in each group. (C) IFN-γ secretion by pooled splenocytes from all animals in each group (black bars) or by pooled splenocytes depleted of CD8 + cells (white bars). M = MVA, D = DNA.

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