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Table 2 Standardized incidence ratios (SIRs) of AIDS- and non-AIDS-defining cancers by study site

From: HIV and cancer: a comparative retrospective study of Brazilian and U.S. clinical cohorts

 

INI

VCCC

N

SIR [95% CI]

N

SIR [95% CI]

AIDS-defining cancers

57

24.6 [18.7-31.9]

47

17.0 [12.5-22.6]

Kaposi Sarcoma

37

269 [189–371]

19

1157 [697–1807]

Non-Hodgkin Lymphoma

20

21.2 [12.9-32.7]

27

11.4 [7.5-16.6]

Cervix

0

0 [0–3.2]

1

2.7 [0.7-14.9]

Non-AIDS-defining cancers

45

1.4 [1.1-1.9]

81

1.3 [1.0-1.7]

Oral Cavity & Pharynx

3

1.7 [0.4-5.0]

2

1.2 [0.1-4.3]

Esophagus

1

1.0 [0–5.4]

1

2.1 [0.1-11.9]

Stomach

2

1.5 [0.2-5.5]

0

0 [0–5.2]

Small Intestine

0

0 [0–47.9]

1

4.2 [0.1-23.6]

Colon & Rectum

2

1.1 [0.1-4.1]

5

1.2 [0.4-2.9]

Anus

7

62.3 [25.1-128]

9

25.0 [11.4-47.5]

Liver

0

0 [0–8.6]

3

3.7 [0.8-10.7]

Biliary Tract

0

0 [0–19.4]

2

17.6 [2.1-63.5]

Pancreas

1

2.9 [0.1-16.1]

0

0 [0–4.8]

Larynx

3

4.6 [0.9-13.3]

2

4.4 [0.5-15.7]

Lung & Bronchus

4

3.0 [0.8-7.7]

11

2.8 [1.4-5.1]

Mediastinum

1

23.0 [0.6-128]

0

0 [0–161]

Soft Tissue Sarcoma

0

0 [0–1.06]

1

2.4 [0.1-13.4]

Squamous and basal cell skin cancers

9

1.9 [0.9-3.7]

28

Not available

Melanoma

0

0 [0–8.1]

2

0.6 [0.1-2.1]

Breast

5

1.3 [0.4-2.9]

1

0.2 [0–1.3]

Corpus Uterus

1

5.5 [0.1-30.8]

0

0 [0–7.7]

Ovary

1

3.0 [0.1-16.5]

1

3.1 [0.1-17.2]

Prostate

1

0.3 [0–1.6]

4

0.4 [0.1-1.0]

Testis

0

0 [0–16.1]

0

0 [0–4.7]

Urinary Bladder

0

0 [0–8.3]

3

2.6 [0.5-7.5]

Kidney

2

4.5 [0.5-16.2]

0

0 [0–2.2]

Brain & other CNS

0

0 [0–4.3]

0

0 [0–4.8]

Thyroid

0

0 [0–8.8]

0

0 [0–2.5]

Other Endocrine

0

0 [0–115]

1

10.0 [0.3-55.5]

Hodgkin Lymphoma

0

0 [0–12.2]

1

1.9 [0.1-10.5]

Myeloma

0

0 [0–12.3]

1

1.6 [0–9.0]

Leukemia

1

1.9 [0.1-10.7]

1

1.0 [0–5.6]

Mesothelioma

0

0 [0–181]

0

0 [0–84.9]

Other

1

1.0 [0–5.3]

1

1.7 [0–9.6]

  1. Comparator population for INI SIRs: Belo Horizonte, MG, general population.
  2. Comparator population for VCCC SIRs: Atlanta, GA, general population.
  3. Abbreviations:
  4. INI: Instituto Nacional de Infectologia Evandro Chagas, Oswaldo Cruz, Rio de Janeiro, RJ, Brazil.
  5. VCCC: Vanderbilt Comprehensive Care Clinic, Nashville, TN, USA.
  6. CI: Confidence interval.