Figure 2
From: Expression of bcl-2 and p53 in bovine cutaneous fibropapillomas
P53 expression in bovine cutaneous fibropapillomas and normal skin; (A) p53 is expressed in the cytoplasm of basal (white arrowhead) and parabasal epithelial cells; note a perinuclear pattern in some cells of the parabasal layer (black arrowhead); (B) Normal skin samples showing a weak p53 cytoplasmic staining, confined to the basal cell layer (white arrow); (C) Epithelial cells of human mammary cancer showed cytoplasmic immunoreactivity (black arrow). IHC, A X 400, B, C X 200.