Evolutionarily new sequences expressed in tumors

Table 2 Summary of cross-species homology analysis results

Sequence/Cluster	Human Position	Compared Genomes where Homology was found*	Aligned Bases between Genomes	% of Aligned Bases**	Matched Bases between Genomes	% of Matched Bases***	Human Sequence		Compared Sequence
							Full length of Aligned Sequence	Unmatched Bases	Full length of Aligned Sequence	Unmatched Bases
AL040372/Hs.133294	chr1:153 308	opossum	965	88.8	505	52.3	1087	582	2068	1563
	314-153	mouse	753	69.3	537	71.3		550	771	234
	309 400	rat	1011	93.0	621	61.4		466	895	274
		cow	964	88.7	701	72.7		386	1916	1215
		dog	1060	97.5	714	67.4		373	1229	515
		rhesus	1086	99.9	1018	93.7		69	1073	55
		chimpanzee	1086	99.9	1071	98.6		16	1077	6
AI792557/HS.133107	chr8:129 160	mouse	401	80.7	242	60.3	497	255	576	334
	366-129	rat	412	82.9	249	60.4		248	561	312
	160 862	cow	418	84.1	279	66.7		218	405	126
		dog	414	83.3	297	71.7		200	624	327
		rhesus	496	99.8	460	92.7		37	488	28
		chimpanzee	496	99.8	486	98.0		11	490	4
AA166653/Hs.426704	chr2:132 864 310-	rhesus	516	86.0	454	88.0	600	146	712	258
	132 864 909	chimpanzee	599	99.8	594	99.2		6	603	9
AI952931/HS. 128594	chr3:54 641	chicken	227	14.0	138	60.8	1624	1486	555	417
	157-54	opossum	256	15.8	185	72.3		1439	262	77
	642 780	mouse	446	27.5	308	69.1		1316	439	131
		rat	658	40.5	420	63.8		1204	624	204
		cow	1330	81.9	980	73.7		644	1415	435
		dog	1302	80.2	977	75.0		647	1318	341
		rhesus	1623	99.9	1516	93.4		108	1635	119
		chimpanzee	1431	88.1	1413	98.7		211	1432	19

* Fugu, tetraodon, zebrafish, frog, chicken, rat, mouse, cow, dog, macaque, and chimpanzee genomes were analyzed.
** Percent of aligned bases were estimated as the ratio of aligned bases between genomes and the full length of the aligned human sequence.
*** Percent of matched bases were estimated as the ratio of matched and aligned bases between genomes.

ISSN: 1750-9378