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Table 2 H. pylori serostatus for different cancer sites or types and non-malignant conditions, together with the percentage of each cancer with laboratory verification of diagnosis

From: Helicobacter pylori and cancer among adults in Uganda

Cancer site or type

Percentage with laboratory verification of diagnosis

Number anti-H. pylori antibody positive/total

Odds ratio (95% CI)1

χ21 and p value

Stomach

90%

18/21

0.8 (0.2–2.9)

χ21 = 0.1, p = 0.7

All controls 2

-

723/833

1.0

-

Oral

56%

21/26

0.6 (0.2–1.7)

χ21 = 0.9, p = 0.4

Oesophagus

45%

37/38

5.1 (0.7–38)

χ21 = 2.5, p = 0.1

Liver

56%

44/52

0.7 (0.3–1.6)

χ21 = 0.8, p = 0.4

Skin

77%

18/22

0.6 (0.2–1.9)

χ21 = 0.8, p = 0.4

Breast

62%

62/69

1.4 (0.6–3.5)

χ21 = 0.6, p = 0.4

Cervix

50%

173/190

1.6 (0.9–2.8)

χ21 = 2.1, p = 0.2

Ovary

73%

20/22

1.1 (0.3–5.0)

χ21 = 0.0, p = 0.9

Prostate

44%

7/10

0.3 (0.1–1.4)

χ21 = 2.4, p = 0.1

Penis

57%

12/14

0.9 (0.2–4.3)

χ21 = 0.0, p = 0.9

Conjunctiva

66%

33/38

1.3 (0.5–3.5)

χ21 = 0.3, p = 0.6

Other eye

52%

22/25

1.1 (0.3–3.9)

χ21 = 0.0, p = 0.9

Non-Hodgkin's lymphoma

76%

39/46

0.8 (0.3–1.8)

χ21 = 0.4, p = 0.5

Hodgkin's lymphoma

83%

20/24

0.6 (0.2–1.9)

χ21 = 0.7, p = 0.4

Kaposi's sarcoma

91%

36/46

0.7 (0.3–1.6)

χ21 = 0.9, p = 0.4

  1. 1. Odds ratios adjusted for age group (<30, 30–45, 46+), sex and HIV serostatus
  2. 2. The comparison group for the calculation of odds ratios includes all other cancers and non-malignant conditions, excluding stomach cancer
  3. Note: H. Pylori serostatus: negative – optical density (O.D.) 0.0–0.8; indeterminate – O.D. 0.9–1.3; positive – O.D. 1.4–4.0. For the purposes of this analysis, those with an indeterminate result were considered to be seronegative.