Clinical oncology

Section edited by: Prof Serigne Magueye Gueye and Prof Jan Vermorken. 

The clinical oncology section represents an opportunity to share experiences and information among worldwide oncologists and to identify and develop diagnostic as well as therapeutic protocols, which are globally valid in the current global village. Potential topics include, but are not limited to: epidemiology, pathology and pathogenesis of cancers and clinical studies

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  1. Research Article

    Safety of new DAAs for chronic HCV infection in a real life experience: role of a surveillance network based on clinician and hospital pharmacist

    Direct Antiviral Agents (DAAs) for HCV therapy represents a step ahead in the cure of chronic hepatitis C. Notwithstanding the promising results in several clinical trials, few data are available on adverse ef...

    A. Nappi, A. Perrella, P. Bellopede, A. Lanza, A. Izzi, M. Spatarella and C. Sbreglia

    Infectious Agents and Cancer 2017 12:12

    Published on: 7 February 2017

  2. Research Article

    Clinical and prognostic analysis of 78 patients with human immuno-deficiency virus associated non-Hodgkin’s lymphoma in Chinese population

    Human Immuno-deficiency Virus (HIV) associated non-Hodgkin’s lymphoma (NHL) was a special group of disease, which manifests distinct clinical features and prognosis as compared with NHLs in patients without HI...

    Yang Shen, Renfang Zhang, Li Liu, Yinzhong Shen, Wei Song, Tangkai Qi, Yang Tang, Zhenyan Wang, Liqian Guan and Hongzhou Lu

    Infectious Agents and Cancer 2017 12:7

    Published on: 23 January 2017

  3. Research Article

    Human papillomavirus infection in anal intraepithelial lesions from HIV infected Cuban men

    An association between HPV infection and progression to anal squamous intraepithelial lesions (ASIL) has been established, specifically in high-risk populations such as HIV-infected men. In this population, an...

    Celia M. Limia, Yudira Soto, Yanara García, Orestes Blanco, Vivian Kourí, María V. López, María E. Toledo, Lissette Pérez, Yoanna Baños, Yaniris Caturla and Francisco Aguayo

    Infectious Agents and Cancer 2017 12:5

    Published on: 17 January 2017

  4. Research Article

    Characterisation of microbial communities within aggressive prostate cancer tissues

    An infectious aetiology for prostate cancer has been conjectured for decades but the evidence gained from questionnaire-based and sero-epidemiological studies is weak and inconsistent, and a causal association...

    Melissa A. Yow, Sepehr N. Tabrizi, Gianluca Severi, Damien M. Bolton, John Pedersen, Graham G. Giles and Melissa C. Southey

    Infectious Agents and Cancer 2017 12:4

    Published on: 13 January 2017

  5. Research Article

    Mouse mammary tumor-like virus (MMTV) is present in human breast tissue before development of virally associated breast cancer

    There is substantial evidence that a virus homologous to mouse mammary tumor virus (MMTV) may have a role in human breast cancer. The present study indicates that those who developed breast cancer associated w...

    Teiko Nartey, Chiara M. Mazzanti, Stella Melana, Wendy K. Glenn, Generoso Bevilacqua, James F. Holland, Noel J. Whitaker, James S. Lawson and Beatriz G.T. Pogo

    Infectious Agents and Cancer 2017 12:1

    Published on: 4 January 2017

  6. Short Report

    Induction of VX2 para-renal carcinoma in rabbits: generation of animal model for loco-regional treatments of solid tumors

    Animal models of para-renal cancer can provide useful information for the evaluation of tumor response to loco-regional therapy experiments in solid tumors. The aim of our study was to establish a rabbit para-...

    Sabrina Bimonte, Maddalena Leongito, Mauro Piccirillo, Maria Luisa Tamma, Marianna Vallifuoco, Adele Bracco, Antonio Mancini, Daniele Di Napoli, Sigismondo Castaldo, Santolo Cozzolino, Francesca Iacobellis, Roberto Grassi, Vincenza Granata, Secondo Lastoria, Steven Curley and Francesco Izzo

    Infectious Agents and Cancer 2016 11:62

    Published on: 1 December 2016

  7. Review

    Molecular mechanisms of HPV mediated neoplastic progression

    Human Papillomavirus is the major etiological agent in the development of cervical cancer but not a sufficient cause. Despite significant research, the underlying mechanisms of progression from a low-grade squ...

    Rashmirani Senapati, Nihar Nalini Senapati and Bhagirathi Dwibedi

    Infectious Agents and Cancer 2016 11:59

    Published on: 25 November 2016

  8. Review

    Multidetector computer tomography in the pancreatic adenocarcinoma assessment: an update

    Ductal adenocarcinoma of the pancreas is one of the most aggressive forms of cancer, with only a minority of cases being resectable at the moment of their diagnosis. The accurate detection and characterization...

    Vincenza Granata, Roberta Fusco, Orlando Catalano, Sergio Venanzio Setola, Elisabetta de Lutio di Castelguidone, Mauro Piccirillo, Raffaele Palaia, Roberto Grassi, Francesco Granata, Francesco Izzo and Antonella Petrillo

    Infectious Agents and Cancer 2016 11:57

    Published on: 15 November 2016

  9. Research Article

    Infection with hepatitis viruses, FIB-4 index and risk of hepatocellular carcinoma in southern Italy: a population-based cohort study

    The incidence of hepatocellular carcinoma (HCC) and its association with hepatitis C (HCV) and hepatitis B virus (HBV) infections, FIB-4 index and liver enzymes was assessed in an area of the province of Naple...

    Mario Fusco, Pierluca Piselli, Saverio Virdone, Pietro Di Cicco, Paola Scognamiglio, Paolo De Paoli, Valerio Ciullo, Diana Verdirosi, Michele D’Orazio, Luigino Dal Maso, Enrico Girardi, Silvia Franceschi and Diego Serraino

    Infectious Agents and Cancer 2016 11:54

    Published on: 3 November 2016

  10. Research Article

    Prevalence of human papillomavirus in saliva of women with HPV genital lesions

    The human papilloma viruses (HPVs) are DNA viruses associated with benign and malignant lesions of skin and mucous membranes. The HPVs has been implicated as the cause of virtually all cervical cancers worldwi...

    Giuseppa Visalli, Monica Currò, Alessio Facciolà, Romana Riso, Placido Mondello, Pasqualina Laganà, Angela Di Pietro, Isa Picerno and Pasquale Spataro

    Infectious Agents and Cancer 2016 11:48

    Published on: 26 August 2016

  11. Research Article

    Fulminant anaplastic large cell lymphoma (ALCL) concomitant with primary cytomegalovirus (CMV) infection, and human herpes virus 8 (HHV-8) infection together with Epstein-Barr-virus (EBV) reactivation in a patient with asymptomatic HIV-infection

    Most malignant lymphomas in HIV-patients are caused by reactivation of EBV-infection. Some lymphomas have a very rapid fulminant course. HHV-8 has also been reported to be a cause of lymphoma. The role of CMV ...

    Sven Grützmeier, Anna Porwit, Corinna Schmitt, Eric Sandström, Börje Åkerlund and Ingemar Ernberg

    Infectious Agents and Cancer 2016 11:46

    Published on: 22 August 2016

  12. Research Article

    Salivary and serum IL-10, TNF-α, TGF-β, VEGF levels in oropharyngeal squamous cell carcinoma and correlation with HPV and EBV infections

    Each year approximately 6,000 new cases of head and neck cancer are registered in Poland. Human papillomavirus (HPV) and Epstein-Barr virus (EBV) have been associated with tumour formation. Cytokines have been...

    Małgorzata Polz-Dacewicz, Małgorzata Strycharz-Dudziak, Jakub Dworzański, Agnieszka Stec and Joanna Kocot

    Infectious Agents and Cancer 2016 11:45

    Published on: 20 August 2016

  13. Research Article

    Variants of human papillomaviruses 16 (HPV16) in Uigur women in Xinjiang, China

    Persistent infection of high-risk human papillomaviruses 16 (HPV16) has been considered as the leading cause of cervical cancer. In this study we assessed HPV16 sequence variation and genetic diversity of HPV1...

    Hongchang He, Hongtao Li, Peiwen Fan, Junling Zhu, Zhenzhen Pan, Huan Pan, Dan Wu, Xianxian Ren, Xiaoqing Guo, Dongmei Li, Zemin Pan and Renfu Shao

    Infectious Agents and Cancer 2016 11:44

    Published on: 18 August 2016

  14. Research Article

    Validation of Novaprep® HQ+ liquid-based cytology medium for high-risk human papillomavirus detection by hc2

    Preanalytical conditions determine the reliability and validity of bioassays. Therefore, the analytic performances of biological tests need to be determined when preanalytical steps differ from those recommend...

    David Guenat, Sophie Launay, Didier Riethmuller, Christiane Mougin and Jean-Luc Prétet

    Infectious Agents and Cancer 2016 11:41

    Published on: 17 August 2016

  15. Research Article

    Establishing and characterizing a new primary effusion lymphoma cell line harboring Kaposi’s sarcoma–associated herpesvirus

    Primary effusion lymphoma is a rare distinct large B-cell neoplasm that is associated with Kaposi’s sarcoma–associated herpesvirus (KSHV) infection. Over recent years, 9 KSHV-positive/Epstein-Barr virus (EBV)-...

    Madori Osawa, Sohtaro Mine, Shinichiro Ota, Kengo Kato, Tsuyoshi Sekizuka, Makoto Kuroda, Michiyo Kataoka, Hitomi Fukumoto, Yuko Sato, Takayuki Kanno, Hideki Hasegawa, Keiji Ueda, Masashi Fukayama, Takuya Maeda, Soichiro Kanoh, Akihiko Kawana…

    Infectious Agents and Cancer 2016 11:37

    Published on: 17 August 2016

  16. Review

    Radio-frequency ablation-based studies on VX2rabbit models for HCC treatment

    Hepatocellular carcinoma (HCC) is the fifth most frequent cancer worldwide with high morbidity, mortality and increasing incidence. It is of note that the main curative therapies for HCC are hepatic resection ...

    Sabrina Bimonte, Maddalena Leongito, Mauro Piccirillo, Cristina de Angelis, Claudia Pivonello, Vincenza Granata and Francesco Izzo

    Infectious Agents and Cancer 2016 11:38

    Published on: 12 August 2016

  17. Research Article

    Human herpesvirus multiplex ddPCR detection in brain tissue from low- and high-grade astrocytoma cases and controls

    Glioblastoma (GBM) is a fatal CNS malignancy, representing 50 % of all gliomas with approximately 12–18 months survival time after initial diagnosis. Recently, the human herpesvirus cytomegalovirus (CMV) has b...

    Cheng-Te Major Lin, Emily C. Leibovitch, M. Isabel Almira-Suarez and Steven Jacobson

    Infectious Agents and Cancer 2016 11:32

    Published on: 26 July 2016

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