From: Trends in gynaecologic cancer mortality and the impact of the COVID-19 pandemic in the United States
Age-standardized Mortality Rate (Per 100,000 Persons) | ||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
 | Age Years | Pre-Pandemic Referent Epoch 2010 | Pre-Pandemic Referent Epoch 2019 | Pandemic Epoch 1 2020 |  | Pandemic Epoch 2 2021 |  | Pandemic Epoch 3 2022 | ||||||
Observed | Predicted [95% CI] | %Increase* | Â | Observed | Predicted [95% CI] | %Increase* | Â | Observed | Predicted [95% CI] | %Increase* | ||||
Gynecologic Cancer†| Overall | 11.109 | 10.160 | 10.491 | 10.011 [9.275–10.746] | + 4.796 |  | 10.677 | 9.677 [8.300-11.054] | + 10.333 |  | 10.596 | 9.185 [6.891–11.478] | + 15.366 |
Age | Â | Â | Â | Â | ||||||||||
25–44 years | 1.673 | 1.627 | 1.682 | 1.613 [1.549–1.676] | + 4.254 |  | 1.882 | 1.605 [1.532–1.678] | + 17.234 |  | 1.63 | 1.598 [1.515–1.681] | + 1.819 | |
45–64 years | 9.425 | 8.807 | 9.125 | 8.769 [7.775–9.763] | + 4.060 |  | 8.968 | 8.476 [6.613–10.338] | + 5.804 |  | 8.889 | 8.050 [4.949–11.151] | + 10.427 | |
≥ 65 years | 36.331 | 32.668 | 33.677 | 32.102 [30.010-34.195] | + 4.905 |  | 34.432 | 30.998 [27.077–34.919] | + 11.077 |  | 34.758 | 29.338 [22.809–35.867] | + 18.474 | |
Ovarian Cancer | Overall | 7.189 | 5.517 | 5.497 | 5.381 [5.257–5.505] | + 2.157 |  | 5.514 | 5.206 [5.064–5.348] | + 5.924 |  | 5.483 | 5.031 [4.871–5.191] | + 8.990 |
Age | Â | Â | Â | Â | ||||||||||
25–44 years | 0.582 | 0.527 | 0.473 | 0.493 [0.410–0.576] | -4.124 |  | 0.473 | 0.481 [0.363–0.598] | -1.732 |  | 0.518 | 0.468 [0.308–0.627] | + 10.713 | |
45–64 years | 5.621 | 4.529 | 4.629 | 4.443 [3.889–4.997] | + 4.178 |  | 4.411 | 4.233 [3.194–5.271] | + 4.199 |  | 4.411 | 3.973 [2.243–5.702] | + 11.018 | |
≥ 65 years | 25.533 | 19.028 | 18.878 | 17.926 [16.801–19.052] | + 5.309 |  | 19.350 | 16.632 [14.524–18.741] | + 16.336 |  | 19.083 | 15.071 [11.560-18.582] | + 26.618 | |
Cervical Cancer | Overall | 2.038 | 1.937 | 2.034 | 1.939 [1.892–1.985] | + 4.921 |  | 2.112 | 1.925 [1.871–1.978] | + 9.730 |  | 1.950 | 1.911 [1.851–1.971] | + 2.025 |
Age | Â | Â | Â | Â | ||||||||||
25–44 years | 0.936 | 0.945 | 1.045 | 0.906 [0.865–0.948] | + 15.38 |  | 1.145 | 0.872 [0.813–0.931] | + 31.346 |  | 0.900 | 0.833 [0.753–0.912] | + 8.028 | |
45–64 years | 2.457 | 2.396 | 2.457 | 2.385 [2.284–2.486] | + 3.034 |  | 2.457 | 2.376 [2.260–2.491] | + 3.428 |  | 2.357 | 2.367 [2.236–2.497] | -0.416 | |
≥ 65 years | 3.898 | 3.471 | 3.624 | 3.452 [3.242–3.662] | + 4.996 |  | 3.786 | 3.400 [3.160–3.640] | + 11.356 |  | 3.711 | 3.348 [3.077–3.620] | + 10.832 | |
Uterine Corpus Cancer | Overall | 1.905 | 2.787 | 3.033 | 2.925 [2.548–3.303] | + 3.678 |  | 3.079 | 2.981 [2.274-3. 689] | + 3.302 |  | 3.211 | 2.962 [1.784–4.139] | + 8.421 |
Age | Â | Â | Â | Â | ||||||||||
25–44 years | 0.109 | 0.209 | 0.209 | 0.169 [0.109–0.229] | + 23.640 |  | 0.264 | 0.176 [0.108–0.245] | + 49.519 |  | 0.209 | 0.184 [0.106–0.261] | + 13.624 | |
45–64 years | 1.386 | 1.982 | 2.139 | 2.037 [1.619–2.454] | + 5.048 |  | 2.100 | 1.973 [1.190–2.756] | + 6.449 |  | 2.161 | 1.824 [0.520–3.128] | + 18.461 | |
≥ 65 years | 7.052 | 10.282 | 11.264 | 10.888 [9.704–12.072] | + 3.453 |  | 11.444 | 11.190 [8.972–13.409] | + 2.271 |  | 12.141 | 11.230 [7.534–14.922] | + 8.116 |