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Fig. 2 | Infectious Agents and Cancer

Fig. 2

From: Engineered small extracellular vesicles as a novel platform to suppress human oncovirus-associated cancers

Fig. 2

Surface engineering of Exos by genetic/biological manipulation or chemical modification. Chemical modifications install various entities, such as peptides, proteins, lipids, aptamers, small molecules, and polymers via chemical reactions or lipid-lipid interactions in lipids or membrane-bound proteins. Biological engineering accordingly introduces targeting motifs, namely, peptides and proteins, through the gene fusion of membrane-bound proteins. DSPE- PEG; 1, 2-distearoyl-sn-glycero-3-phosphoethanolamine-polyethylene glycol, scFvs; single-chain variable fragments, Ab; antibody, LAMP; lysosome-associated membrane protein, PDGFR; platelet-derived growth factor receptor

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