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Table 1 Baseline characteristics of 439 women undergoing colposcopy in the Second Xiangya Hospital of Central South University according to the degree of cervical lesions

From: Association between co-infection with Chlamydia trachomatis or Mycoplasma genitalium and cervical lesions in HPV-positive population in Hunan, China: a cross-sectional study

Variables

All (n = 439)

NO SIL (n = 204)

LSIL (n = 127)

≥HSIL (n = 108)

P value

Age, years, median (IQR)

439

45.00 (36.00–53.00)

204

46.00 (37.25-53.00)

127

45.00 (34.00–53.00)

108

41.00 (35.00-52.75)

0.437

19–30, n (%)

 

49 (11.16)

 

20 (9.80)

 

20 (9.80)

 

14 (12.96)

0.421

31–40, n (%)

 

116 (26.42)

 

50 (24.51)

 

50 (24.51)

 

34 (31.48)

 

41–50, n (%)

 

119 (27.11)

 

59 (28.92)

 

59 (28.92)

 

27 (25.00)

 

51–60, n (%)

 

130 (29.61)

 

68 (33.33)

 

68 (33.33)

 

24 (22.22)

 

> 60, n (%)

 

25 (5.69)

 

7 (3.43)

 

7 (3.43)

 

9 (8.33)

 

History of pregnancy, n (%)

439

 

204

 

127

 

108

  

Yes

 

409 (93.17)

 

193 (94.61)

 

114 (89.76)

 

102 (94.44)

0.197

No

 

30 (6.83)

 

11 (5.39)

 

13 (10.24)

 

6 (5.56)

 

Number of pregnancy, n (%)

423

 

197

 

121

 

105

  

0

 

30 (7.09)

 

11 (5.58)

 

13 (10.72)

 

6 (5.71)

0.376

1

 

50 (11.82)

 

24 (12.18)

 

15 (12.40)

 

11 (10.48)

 

2

 

93 (21.99)

 

41 (20.81)

 

24 (19.83)

 

28 (26.67)

 

3

 

85 (20.09)

 

38 (19.29)

 

27 (22.31)

 

20 (19.05)

 

4

 

75 (17.73)

 

36 (18.27)

 

18 (14.88)

 

21 (20.00)

 

≥ 5

 

90 (21.28)

 

47 (23.86)

 

24 (19.83)

 

19 (18.10)

 

History of production, n (%)

439

 

204

 

127

 

108

  

Yes

 

385 (87.70)

 

183 (89.71)

 

106 (83.46)

 

96 (88.89)

0.222

No

 

54 (12.30)

 

21 (10.29)

 

21 (16.54)

 

12 (11.11)

 

Parity, n (%)

424

 

197

 

122

 

105

  

0

 

54 (12.74)

 

21 (10.66)

 

21 (17.21)

 

12 (11.43)

0.435

1

 

173 (40.80)

 

93 (47.21)

 

41 (33.61)

 

39 (37.14)

 

2

 

156 (36.79)

 

65 (32.99)

 

50 (40.98)

 

41 (39.05)

 

≥ 3

 

41 (9.67)

 

18 (9.14)

 

10 (8.20)

 

13 (12.38)

 

Menopause, n (%)

439

 

204

 

127

 

108

  

Yes

 

164 (37.36)

 

79 (38.73)

 

47 (37.01)

 

38 (35.19)

0.824

No

 

275 (62.64)

 

125 (61.27)

 

80 (62.99)

 

70 (64.81)

 

Leukocyte level, n (%)

432

 

203

 

124

 

105

  

0–15/HP

 

217 (50.23)

 

114 (56.16)

 

53 (42.74)

 

50 (47.62)

0.042

16–30/HP

 

175 (40.51)

 

75 (36.94)

 

58 (46.78)

 

42 (40.00)

 

> 30/HP

 

40 (9.26)

 

14 (6.90)

 

13 (10.48)

 

13 (12.38)

 

HPV infection types, n (%)

419

 

196

 

124

 

99

  

Single infection

 

314 (74.94)

 

146 (74.49)

 

87 (70.16)

 

81 (81.82)

0.134

Multiple infection

 

105 (25.06)

 

50 (25.51)

 

37 (29.84)

 

18 (18.18)

 

Cervical cytology test, n (%)

439

 

204

 

127

 

108

 

< 0.001

NILM

 

274 (62.41)

 

167 (81.86)

 

69 (54.34)

 

38 (35.18)

 

ASC-US

 

98 (22.32)

 

26 (12.75)

 

41 (32.28)

 

31 (28.70)

 

ASC-H

 

11 (2.51)

 

0 (0.00)

 

0 (0.00)

 

11 (10.19)

 

LSIL

 

37 (8.43)

 

11 (5,39)

 

15 (11.81)

 

11 (10.19)

 

HSIL

 

19 (4.33)

 

0 (0.00)

 

2 (1.57)

 

17 (15.74)

 

CT, n (%)

439

17 (3.87)

204

10 (4.90)

127

3 (2.36)

108

4 (3.70)

0.505

MG, n (%)

439

16 (3.64)

204

10 (4.90)

127

3 (2.36)

108

3 (2.78)

0.418

  1. Data are presented as the Median (IQR: Q1–Q3) for continuous variables that are not normally distributed and percentage for categorical variables. The Chi-square test or nonparametric Kruskal-Wallis test were used for statistical comparisons between three groups. P value ≤ 0.05 was considered statistically significant
  2. NILM: Negative for intraepithelial lesion or malignancy; ASC-US: Atypical squamous cells of undetermined significance; ASC-H: Atypical squamous cells: cannot exclude high-grade squamous intraepithelial lesion; LSIL: Low-grade squamous intraepithelial lesion; HSIL: High-grade squamous intraepithelial lesion; IQR: interquartile range; CT: Chlamydia trachomatis; MG: Mycoplasma genitalium