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Fig. 2 | Infectious Agents and Cancer

Fig. 2

From: IGFBP2 drives epithelial-mesenchymal transition in hepatocellular carcinoma via activating the Wnt/β-catenin pathway

Fig. 2

IGFBP2 drives EMT to promote invasion and metastasis in HCC cells. A Expression of IGFBP2 in HCC cells was detected by immunofluorescence. Scale bars, 50 μm. B Effect of IGFBP2 overexpression on the migration and invasion of HCC cells. Scale bars, 50 μm. C Effect of IGFBP2 on the expression of EMT related proteins in HCC cells was detected by western blot. D Effect of IGFBP2 on the expression of EMT related proteins in HCC cells was detected by immunofluorescence. Scale bars, 50 μm. E Effect of IGFBP2 on the expression of EMT related genes in HCC cell lines were detected by RT-PCR. *p < 0.05 versus HepG2/pcDNA3.1-Ctr, **p < 0.01 versus HepG2/pcDNA3.1-Ctr

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