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Table 2 CIN 3 + risk of different cytology results in HPV 16/18-positive women (n = 6533)

From: Risk of cervical intraepithelial neoplasia grade 3 or more diagnoses for human papillomavirus16/18-positive women by cytology and co-infection status

HPV genotype

Cytology

CIN 3 + cases, No. (%)

Total

P Value

HPV 16

NILM

248 (11.4)

2185

 < 0.001

ASC-US

268 (23.2)

1157

LSIL

205 (28.8)

713

ASC-H

211 (72.3)

292

AGC

70 (66.0)

106

HSIL + 

623 (89.9)

693

HPV 18

NILM

38 (4.8)

799

 < 0.001

ASC-US

40 (10.3)

388

LSIL

23 (10.7)

214

ASC-H

17 (34.7)

49

AGC

36 (72.0)

50

HSIL + 

79 (82.3)

96

  1. HPV human papillomavirus, CIN 3 + cervical intraepithelial neoplasia grade 3 or more severe diagnoses, NILM negative for intraepithelial lesions or malignancy, ASC-US atypical squamous cells of undetermined significance, LSIL low-grade intraepithelial lesion, ASC-H atypical squamous cells cannot exclude high-grade squamous intraepithelial lesion, AGC atypical glandular cells, HSIL + high-grade squamous intraepithelial lesion or worse