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Table 1 Distribution of HPV 16/18 infection patterns among the study population (n = 7940)

From: Risk of cervical intraepithelial neoplasia grade 3 or more diagnoses for human papillomavirus16/18-positive women by cytology and co-infection status

HPV16/18 infection patterns

No. (%)

P Value

Normal

CIN 1

CIN 2

CIN3/AIS

Cancer

Total

HPV 16 only

1959 (47.1)

373 (9.0)

420 (10.1)

937 (22.5)

471 (11.3)

4160 (100)

< 0.001

HPV 16 + other hrHPVs

584 (45.9)

176 (13.8)

171 (13.5)

272 (21.4)

68 (5.4)

1271 (100)

HPV 16 + lrHPVs

177 (53.3)

41 (12.3)

43 (13.0)

49 (14.8)

22 (6.6)

332 (100)

HPV 16 + lrHPVs + other hrHPVs

147 (52.1)

57 (20.2)

41 (14.5)

29 (10.3)

8 (2.8)

282 (100)

HPV 18 only

688 (64.4)

152 (14.2)

79 (7.4)

65 (6.1)

84 (7.9)

1068 (100)

0.266

HPV 18 + other hrHPVs

253 (59.0)

80 (18.6)

44 (10.3)

39 (9.1)

13 (3.0)

429 (100)

HPV 18 + lrHPVs

76 (67.9)

21 (18.8)

6 (5.4)

7 (6.3)

2 (1.8)

112 (100)

HPV 18 + lrHPVs + other hrHPVs

71 (59.2)

30 (25.0)

12 (10.0)

6 (5.0)

1 (0.8)

120 (100)

HPV 16 + HPV 18

34 (41.5)

7 (8.5)

14 (17.1)

13 (15.9)

14 (17.1)

82 (100)

0.068

HPV 16 + HPV 18 + other hrHPVs

22 (43.1)

9 (17.6)

6 (11.8)

11 (21.6)

3 (5.9)

51 (100)

HPV 16 + HPV 18 + lrHPVs

9 (60.0)

5 (33.3)

1 (6.7)

0 (0.0)

0 (0.0)

15 (100)

HPV 16 + HPV 18 + lrHPVs + other hrHPVs

8 (44.4)

5 (27.8)

3 (16.7)

2 (11.1)

0 (0.0)

18

  1. HPV human papillomavirus, CIN cervical intraepithelial neoplasia, AIS adenocarcinoma in situ, other hrHPVs high-risk HPV 26/31/33/35/39/45/51/52/53/56/58/59/66/68/73/82, lrHPVs low-risk HPV 6/11/40/42/43/44/55/61/81/83