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Table 1 Demographics and other characteristics by year of serum collection (N = 7576)

From: Epstein–Barr virus (EBV) antibody changes over time in a general population cohort in rural Uganda, 1992–2008

 

1992

(n = 3081)

2000

(n = 3000)

2008

(n = 2996)

Age–mean [std]

26.6 [19.9]

26.4 [20.1]

26.1 [21.0]

Sex–n (%)

   

 Male

1476 (47.9)

1500 (50.0)

1497 (50.0)

 Female

1605 (52.1)

1500 (50.0)

1499 (50.0)

KSHV serostatus1–n (%)

   

 Negative

286 (9.3)

180 (6.0)

312 (10.4)

 Positive

2795 (90.7)

2820 (94.0)

2684 (89.6)

EBV serostatus2–n (%)

   

 Negative

205 (6.7)

149 (5.0)

200 (6.7)

 Positive

2876 (93.3)

2851 (95.0)

2796 (93.3)

HIV serostatus–n (%)

   

 Negative

2868 (93.1)

2687 (89.6)

2750 (91.8)

 Positive

190 (6.2)

184 (6.1)

192 (6.4)

CD4 T cell count (per mm3)3–mean [std]

898 [428]

931 [851]

638 [353]

WHO HIV disease stage4–n (%)

   

 1 (asymptomatic/acute retroviral syndrome)

24 (32.0)

22 (17.9)

23 (16.4)

 2

23 (30.7)

25 (20.3)

41 (29.3)

 3

21 (28.0)

64 (52.0)

59 (42.1)

 4 (most severe disease)

7 (9.3)

12 (9.8)

17 (12.1)

  1. EBV Epstein–Barr virus, HIV Human immunodeficiency virus, KSHV Kaposi’s sarcoma-associated herpesvirus, WHO World Health Organization
  2. 1KSHV seropositivity was defined as detection of antibodies to KSHV K8.1 or ORF73 (LANA) measured by ELISA
  3. 2EBV seropositivity was determined by detection of anti-EBV IgG antibodies to either EBNA-1, EAd, or VCA measured by multiplex bead-based assay
  4. 3CD4 T Cell Count available in 1992, 2000, and 2008 for n = 50, n = 122, and n = 136, respectively
  5. 4WHO HIV disease stage was available in 1992, 2000, and 2008 for n = 75, n = 123, and n = 140, respectively