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Table 3 Genotype and allele distribution frequencies in cases and controls

From: Impact of NLRP3 gene polymorphisms (rs10754558 and rs10733113) on HPV infection and cervical cancer in southern Chinese population

SNP

Genotype

Cases(n = 404)

Controls(n = 419)

P value

OR (95%CI)

rs10754558

CC

130(32.18)

166(39.62)

 

1.000

 

CG

220(54.45)

215(51.31)

0.077

1.307(0.971–1.758)

 

GG

54(13.37)

38(9.07)

0.013

1.815(1.129–2.916)

 

CG + GG

274(67.82)

253(60.38)

0.026

1.383(1.039–1.841)

 

GG

54(13.37)

38(9.07)

 

1.000

 

CG + CC

350(86.63)

381(90.93)

0.052

0.646(0.416–1.003)

 

C Allele

480(59.41)

547(65.27)

 

1.000

 

G Allele

328(40.59)

291(34.73)

0.014

1.284(1.052–1.569)

rs10733113

GG

279(69.06)

291(69.45)

 

1.000

 

GA

104(25.74)

106(25.30)

0.886

1.023(0.746–1.404)

 

AA

21(5.20)

22(5.25)

0.989

0.996(0.536-0.851)

 

GA + AA

125(30.94)

128(30.55)

0.903

1.019(0.757–1.370)

 

AA

21(5.20)

22(5.25)

 

1.000

 

GA + GG

383(94.80)

397(94.75)

0.973

1.011(0.547–1.868)

 

G Allele

662(81.93)

688(82.10)

 

1.000

 

 A Allele

146(18.07)

150(17.90)

0.929

1.012(0.787–1.301)

  1. Cases, including cervical cancer and cervical intraepithelial neoplasia