Table 5 Analysis of clinical factors and laboratory factors between the vaccinated and non-vaccinated patients

Age (y, mean ± SD)

67.87 ± 10.78

67.76 ± 5.5

0.945

Sex

0.729

Male

68

23

Female

11

2

ECOG

0.006

0–1

55

24

> 1

24

1

History

1

Squamous

27

9

Non-squamous

52

16

Smoking status

0.713

Smoker

42

15

Nonsmoker

37

10

Disease stage

0.161

III

13

8

IV

66

17

Treatment line

0.004

First line

35

20

Subsequent lines

44

5

DCR

54.43%(43)

88%(22)

0.005

ORR

11.39%(9)

28%(7)

0.050

CD3+ (%)

72.06(61.05,77.42)

71.35(62.875, 74.6)

0.850

CD4+ (%)

38.69 ± 11.60

43.71 ± 6.99

0.047

CD8+ (%)

25.23(20.76,30.10)

20.60(16.55,23.75)

0.049

CD4/CD8

1.68(0.97,2.01)

2.11(1.90,3.85)

0.025

CD16 + 56+ (%)

17.31 ± 8.56

13.70 ± 9.21

0.182

CD19+ (%)

7.7(4.8,10.63)

10.97(6.63,15.78)

0.069

IgM (g/L)

0.84(0.71,1.14)

0.85(0.67,1.09)

0.642

IgG (g/L)

12.40(9.80,13.95)

12.30(10.31,13.25)

0.747

IgA (g/L)

2.36(1.82,3.01)

2.51(2.27,2.79)

0.832

IgE (g/L)

38.7(22.13,105.00)

115(23.80,157)

0.449

IgM(g/L)

0.84(0.71,1.14)

0.85(0.67,1.09)

0.642

Transferrin

1.55 ± 0.39

1.79 ± 0.25

0.019

Eosinophil

0.11(0.05,0.205)

0.17(0.06,0.30)

0.057

NLR (g/L)

4.02(2.79,7.42)

3.28(2.63,5.36)

0.177

Fibrinogen (g/L)

4.24(3.29,5.33)

3.90(2.96,4.90)

0.675

D-Dimer (mg/L)

1.38(0.70,3.29)

1.18(0.67,1.63)

0.302