Table 3 Association of B. fragilis with signaling pathway genes and clinicopathological characteristics
Characteristics (numbers (%)) | Correlation with B. fragilis (P value) | |||
|---|---|---|---|---|
Clinicopathological | Age | < 50 | 6 (20%) | > 0.05 |
> 50 | 24 (80%) | > 0.05 | ||
Sex | Male | 15 (50) | > 0.05 | |
Female | 15 (50) | |||
Stage | I | 4 (13.3%) | > 0.05 | |
II | 23 (76.7%) | |||
III | 2 (6.7%) | |||
IV | 1 (3.3%) | |||
Histology | Adenocarcinoma | 27 (90%) | > 0.05 | |
Mucinous | 3 (10%) | |||
Site of primary | Colon | 20 (66.7%) | > 0.05 | |
Rectal | 10 (33.3%) | |||
Drinkers | 4 (13.3%) | > 0.05 | ||
Smokers | 3 (10%) | > 0.05 | ||
Signaling genes | WNT/ β-catenin signaling pathway | WNT | > 0.05 | |
TCF | > 0.05 | |||
APC | > 0.05 | |||
CTNNB1 | < 0.05 | |||
AXIN | < 0.05 | |||
Apoptotic Pathways | CCND1 | > 0.05 | ||
BCL2 | < 0.05 | |||
BAX | > 0.05 | |||
TP53 | > 0.05 | |||