Title | First author | Year | Conclusion | T. vaginalis causes cancer |
---|---|---|---|---|
Infection and cervical intraepithelial neoplasia | Boyle DC | 1999 | The risk of cervical neoplasia in the presence of T. vaginalis is about twice that in normal, which may be related to the production of nitrosamine | Yes |
Trichomonas vaginalis: paradigm of a successful sexually transmitted organism | Rughooputh S | 2005 | T. vaginalis can be classified as one of the most important auxiliary factors in the pathogenesis of cervical cancer | Yes |
Sexually transmitted infections and risk of prostate cancer: review of historical and emerging hypotheses | Sutcliffe S | 2014 | T. vaginalis promotes prostate cancer through an IgE mediated anti flagellar hormone inflammatory immune mechanism, while T. vaginalis may promote cancer by directly damaging or dissolving prostate epithelial cells | Yes |
Association of Genital Infections Other Than Human Papillomavirus with Pre-Invasive and Invasive Cervical Neoplasia | Ghosh I | 2016 | T. vaginalis infection has a higher risk of cervical precancerous lesions and neoplastic lesions | Yes |
The dawn of novel STI prevention methods: modelling potential unintended effects of changes in cervical cancer screening guidelines on trichomoniasis | Rönn MM | 2018 | Patients infected with hrHPV are more likely to be infected with T. vaginalis than those not infected with hrHPV | Yes |