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Table 1 The information of relevant epidemiological articles

From: The correlation between Trichomonas vaginalis infection and reproductive system cancer: a systematic review and meta-analysis

Number

Title

First author

Year

Location

Total sample

Experimental group

Control group

Nos

1

An epidemiologic study of carcinoma in situ and squamous dysplasia of the uterine cervix

Thomas DB

1973

USA

626

49/324 (15.1%)

18/302 (6.0%)

8

2

The association of sexually transmitted diseases with cervical intraepithelial neoplasia: a case–control study

Guijon FB

1985

Canada

84

1/32 (3%)

1/52 (2%)

6

3

Vaginal microbial flora as a cofactor in the pathogenesis of uterine cervical intraepithelial neoplasia

Guijon F

1992

Canada

185

4/106 (3.8%)

4/79 (5.1%)

8

4

The association between sexually transmitted pathogens and cervical intra-epithelial neoplasia in a developing community

Kharsany AB

1993

Durban

48

11/28 (39%)

3/20 (15%)

6

5

Trichomonas vaginalis and cervical cancer. A prospective study in China

Zhang ZF

1995

China

16,797

7/421 (1.7%)

92/16376 (0.6%)

7

6

Atypical squamous cells of undetermined significance: Bethesda classification and association with Human Papillomavirus

Barcelos AC

2011

Brazil

170

4/140 (2.85%)

0/30 (0)

6

7

Prospective study of effect modification by Toll-like receptor 4 variation on the association between Trichomonas vaginalis serostatus and prostate cancer

Chen YC

2013

USA

1382

71/690 (10%)

61/692 (9%)

6

8

Bacterial vaginosis, aerobic vaginitis, vaginal inflammation and major Pap smear abnormalities Prevalence of human papillomavirus and co-existent sexually transmitted

Vieira P

2016

Portugal

1244

31/905 (3.4%)

11/339 (3.2%)

6

9

Prevalence of human papillomavirus, Chlamydia trachomatis, and Trichomonas vaginalis infections in Amazonian women with normal and abnormal cytology

Costa-Lira

2017

Brazil

180

0/47 (0)

24/133 (18%)

6

10

Correlation between Common Lower Genital Tract Microbes and High-Risk Human Papillomavirus Infection

Panpan Lv

2019

China

826

8/254 (3.1%)

1/572 (0.2%)

6

11

Prevalence of human papillomavirus, human immunodeficiency virus and other sexually transmitted infections among female sex workers in Togo: a national cross-sectional survey

Ferré VM

2019

Togo

310

9/102 (8.8%)

11/208 (5.3%)

6

12

Association between Trichomonas vaginalis infection and cervical lesions: a population-based, nested case–control study in Taiwan

Su RY

2020

Taiwan

270,015

12/54003 (0.02%)

18/216012 (0.008%)

6

13

Trichomonas vaginalis serostatus and prostate cancer risk in Egypt: a case–control study

Saleh NE

2021

Egypt

445

57/325 (17.5%)

10/120 (8.3%)

6

14

Prevalence of cervical HPV infection, sexually transmitted infections and associated antimicrobial resistance in women attending cervical cancer screening in Mali

Jary A

2021

Mali

144

7/90 (7.8%)

3/54 (5.6%)

7

15

Infection with Trichomonas vaginalis in a black population

Miller JM

1989

USA

3005

140/745 (18.8%)

169/2260 (7.5%)

6

16

Gynaecological infections as risk determinants of subsequent cervical neoplasia

Viikki M

2000

Finland

19,114

16/1544 (1.0%)

82/17600 (0.5%)

6

17

Association of Chlamydia trachomatis with persistence of high-risk types of human papillomavirus in a cohort of female adolescents

Samoff E

2005

USA

261

7/18 (39%)

83/234 (35.8%)

6

18

Results of longterm hospital based cytological screening in asymptomatic women

Misra JS

2006

India

20,417

54/671 (8.1%)

485/19746 (2.5%)

6

19

Human Papillomaviruses and genital co-infections in gynaecological Outpatients

Verteramo R

2008

Italy

857

3/10 (0.3%)

263/847 (1.2%)

7

20

Prevalence and risk factors for cervical neoplasia: a cervical cancer screening program in Beijing

Tao L

2014

China

748,105

9/5104 (1.8%)

504/697064 (0.07%)

6

21

Association between high risk human papillomavirus infection and co-infection with Candida spp. and Trichomonas vaginalis in women with cervical premalignant and malignant lesions

Ghosh I

2017

India

225

130/177 (73.4%)

27/48 (56.2%)

6

22

Trichomonas vaginalis as a risk factor for human papillomavirus: a study with women undergoing cervical cancer screening in a northeast region of Brazil

Belfort IKP

2021

Brazil

562

21/107 (20%)

27/455 (5.9%)

7

  1. 1–14 Experimental group: the number (incidence) of T. vaginalis infection among patients with cancer; Control group: the number (incidence) of T. vaginalis infection among people without cancer. 15–22 Experimental group: the number (incidence) of cancer among people with T. vaginalis infection; Control group: the number (incidence) of cancer among people without T. vaginalis infection