Is the HERV-K HML-2 Xq21.33, an endogenous retrovirus mutated by gene conversion of chromosome X in a subset of African populations, associated with human breast cancer?

Table 5 Mutations in the env region of HERV-K HML-2 Xq21.33 (Acc. No. KU054272.1)

Possible first conversion events
5370 T to A Nigerian, Ghanaian, African Americans, Pygmy Cell line HCC (found in complete sequences from 5355 to 9472)	30/30
8529 A to G Nigerian, Ghanaian, African Americans, Pygmy Cell line HCC and DT22 (found in complete sequences from 5355 to 9472 and from about 5390 to 9472)	46/46
7596 T to C Nigerian, Ghanaian, African Americans, Pygmy Cell line DT22 only	25/46
Possible second conversion events
Nigerians only 5370, 8529 and 7596 + 5735 C to T, 6089 C to T, 6345 C to T 7274 A to G, 7795 G to A, 8914 T to C	2/2
Ghanaians only 5370, 8529 and 7596 + 6914 C to T, 7203 G to A, 8170 A to G, 8600 C to A	2/2

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