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Table 3 Survival rates according to clinical and pathological data

From: HPV infection and p53 and p16 expression in esophageal cancer: are they prognostic factors?

Variable

Progression-free survival

Specific survival

Total events

One-year

p-value

Total events

One-year

p-value

Sex

 Female

4

86.7

0.050

14

72.3

0.025

 Male

35

63.3

 

79

49.8

 

Age at diagnosis

  ≤ 60 years old

18

73.3

0.553

45

54.9

0.266

  > 60 years old

21

63.0

 

48

53.2

 

Alcohol consumption

  ≤ 20 years

5

74.6

0.218

16

62.0

0.301

  > 20 years

34

66.9

 

77

52.0

 

Tobacco consumption

  ≤ 20 years

11

51.3

0.158

19

49.0

0.796

  > 20 years

28

73.1

 

74

55.3

 

Clinical stagea

 I or II

6

91.2

0.019

13

78.6

<0.001

 III or IV

32

57.9

 

73

44.2

 

Histological gradea

 Well differentiated

4

76.2

0.170

10

63.5

0.426

 Moderately differentiated

18

72.4

 

55

48.8

 

Poorly differentiated

15

57.4

 

26

61.4

 

Surgery

 No

32

65.8

0.486

84

47.5

<0.001

 Yes

7

80.0

 

9

85.4

 

Chemoradiotherapy

 No

8

72.4

0.731

24

34.6

0.039

 Chemo or Radio

15

62.3

 

36

47.7

 

 Chemo and Radio

16

72.9

 

33

69.1

 

HPVa

 Negative

23

69.3

0.885

56

52.6

0.093

 Positive

3

71.4

 

11

31.3

 

p16a

 Negative

35

66.9

0.956

84

52.4

0.739

 Positive

4

75.2

 

9

60.6

 

p53a

 Negative

12

66.3

0.892

27

51.4

0.584

 Positive

26

67.0

 

63

54.9

 
  1. aThere are missing values
  2. Entries in boldface are significantly different