Table 1 Fraction of cancers attributable to all HPV types and to 9-valent HPV vaccine typesa by cancer site
Cancer site | ICD-10 code | Fraction attributable to all HPV types % [95% CI]b | Fraction attributable to 4-valent HPV vaccine types (6/11/16/18) % [95% CI]b | Fraction attributable to 9-valent HPV vaccine types (6/11/16/18/31/33/45/52/58) % [95% CI]b | Reference |
|---|---|---|---|---|---|
Cervix | C53 | 100c | 72.9 [71.0-74.8] | 89.1 [87.7-90.4] | [13] |
Vulva | C51 | 15.9 [13.5-18.4] | 84.4 [77.3-90.0] | 94.3 [89.1-97.5] | [14] |
Vagina | C52 | 70.2 [62.2-77.4] | 72.6 [63.1-80.9] | 87.1 [78.8-92.6] | [16] |
Anus | C21 | 87.1 [81.0-91.8] | 91.5 [85.7-95.6] | 94.4 [89.2-97.5] | [15] |
Penis | C60 | 29.0 [24.7-33.7] | 78.9 [70.6-85.9] | 90.7 [84.1-95.3] | [7] |
Oral cavity | C02-06 | 3.7 [2.4-5.6] | 90.9 [70.8-98.9] | 90.9 [70.8-98.9] | [6] |
Nasopharynx | C11 | 10.8 [3.0-25.4] | 75.0 [19.4-99.4] | 75.0 [19.4-99.4] | [6] |
Oropharynx | C01, C09, C10 | 19.9 [17.2-22.8] | 93.8 [88.8-97.0] | 97.5 [93.7-99.3] | [6] |
Hypopharynx | C12-13 | 2.4 [0.3-8.4] | 50.0 [1.3-98.7] | 100 [15.8-100] | [6] |
Pharynx | C14 | 25.0 [10.7-44.9] | 85.7 [42.1-99.6] | 85.7 [42.1-99.6] | [6] |
Larynx | C32 | 2.4 [1.2-4.1] | 66.7 [34.9-90.1] | 91.7 [61.5-99.8] | [6] |