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Table 4 Risk allele load and risk for Squamous Intraepithelial Cervical Lesions (SICL)

From: The SNP at −592 of human IL-10 gene is associated with serum IL-10 levels and increased risk for human papillomavirus cervical lesion development

Number of alleles associated with SICL

n

ORa.

CI 95%

P Value*

Total

SICL

NCL

0

372

174

198

1

-

 

1

280

127

153

1.07

0.78-1.47

0.66

2

38

17

21

1.17

0.58-2.33

0.65

≥3

50

14

36

2.58

1.33-5.00

0.005

Trend p value

0.014

  1. n = Number of alleles.
  2. a. OR adjusted by age and HPV genotype.
  3. *p < 0.05.