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Table 3 Toxicological and Biochemical Biomarkers for Control, MNU, BCG and P-MAPA groups

From: Effects of P-MAPA Immunomodulator on Toll-Like Receptors and p53: Potential Therapeutic Strategies for Infectious Diseases and Cancer

Parameters

Control

MNU

BCG

P-MAPA

(n = 10)

(n = 10)

(n = 10)

(n = 10)

ALT (U/L)

49.23 ± 1.61

46.03 ± 0.63

46.30 ± 3.60

51.61 ± 7.07

AST (U/L)

189.72 ± 28.74

133.05 ± 2.29

201.61 ± 23.84

208.38 ± 31.34

Alkaline Phosfatase (U/L)

42.97 ± 0.87a

128.11 ± 8.21

38.88 ± 3.51a

40.56 ± 3.93a

Urea (mg/dL)

55.45 ± 3.90a

163.09 ± 14.14

60.52 ± 5.90a

57.32 ± 7.16a

Creatinine (mg/dL)

1.18 ± 0.26a

10.33 ± 0.10

1.22 ± 0.25a

1.94 ± 1.24a

  1. Data expressed as mean ± SEM, p < 0.05; Letter a: significantly different from MNU group. MNU = n-methyl-n-nitrosourea; BCG = Bacillus Calmette-Guerin.