From: HPV16 variant lineage, clinical stage, and survival in women with invasive cervical cancer
TRAIT | CATEGORY | 16-EP (%1) n = 52 | 16-EV (%1) n = 20 | 16-EV-G (%1) n = 47 | Total (%2) n = 119 | P-VALUE3 |
---|---|---|---|---|---|---|
 | Non-keratinizing | 26 (41.9) | 12 (19.4) | 24 (38.7) | 62 (57.4) |  |
CELL TYPE | Keratinizing | 21 (45.7) | 5 (10.9) | 20 (43.5) | 46 (42.6) | 0.53 |
 | Squamous, NOS4 | 5 - | 3 - | 3 - | 11 - |  |
AGE GROUP | 20-40 | 15 (37.5) | 5 (12.5) | 20 (50.0) | 40 (33.6) | Â |
 | 41-50 | 20 (45.5) | 11 (25.0) | 13 (29.5) | 44 (37.0) | 0.26 |
 | 51-72 | 17 (48.6) | 4 (11.4) | 14 (40.0) | 35 (29.4) |  |
RACE | White | 44 (45.8 | 15 (15.6) | 35 (38.5) | 94 (76.1) | Â |
 | Black | 2 (50.0) | 2 (50.0) | 0 | 4 (3.4) | 0.07 |
 | Hispanic | 2 (28.6) | 0 | 5 (71.4) | 7 (5.9) |  |
 | Native American | 3 (30.0) | 1 (10.0) | 6 (60.0) | 10 (8.5) |  |
 | Asian | 1 (50.0) | 1 (50.0) | 0 | 2 (1.7) |  |
 | Other | 0 - | 1 (100) | 0 | 1 (0.8) |  |
 | ND5 | 0 - | 0 - | 1 - | 1 - |  |
 | 1A | 6 (42.9) | 2 (14.3) | 6 (42.9) | 14 (12.2) |  |
STAGE (FIGO) | 1B1 | 16 (44.4) | 8 (22.2) | 12 (33.3) | 36 (31.3) | 0.75 |
 | 1B2 | 4 (28.6) | 3 (21.4) | 7 (50.0) | 14 (12.2) |  |
 | 2 | 10 (45.5) | 1 (4.5) | 11 (50.0) | 22 (19.1) |  |
 | 3 | 9 (50.0) | 3 (16.7) | 6 (33.3) | 18 (15.6) |  |
 | 4 | 5 (45.5) | 3 (27.3) | 3 (27.3) | 11 (9.6) |  |
 | Recurrent/Unstaged | 2 - | 0 - | 2 - | 4 - |  |
 | 0 | 4 (80.0) | 0 - | 1 (20.0 | 5 (4.3) |  |
GRAVIDITY | 1-3 | 24 (35.8) | 11 (16.4) | 32 (47.8) | 67 (57.8) | 0.18 |
 | >3 | 22 (50.0) | 9 (20.5) | 13 (29.5) | 44 (37.9) |  |
 | ND5 | 2 - | 0 - | 1 - | 3 - |  |
PARAMETRIA6 | Negative | 20 (43.5) | 8 (17.4) | 18 (39.1) | 46 (53.5) | Â |
 | Positive | 19 (47.5) | 6 (15.0) | 15 (37.5) | 40 (46.6) | 0.92 |
 | ND | 13 - | 6 - | 14 - | 33 - |  |
Table 2 (cont'd) | Â | Â | Â | Â | Â | Â |
 | <1 | 6 (40.0) | 2 (13.3) | 7 (46.7) | 15 (14.7) |  |
TUMOR SIZE6 (cm) | 1-4 | 18 (46.2) | 7 (17.9) | 14 (35.9) | 39 (38.2) | 0.96 |
 | >4 | 21 (43.8) | 7 (14.6) | 20 (41.7) | 48 (47.1) |  |
 | ND | 7 - | 4 - | 6 - | 17 - |  |
 | < 3 | 3 (23.1) | 2 (15.4) | 8 (61.5) | 13 (22.0) |  |
INVASION DEPTH 7 | 3.1 - 5.0 | 5 (62.5) | 0 | 3 (37.5) | 8 (13.3) | 0.24 |
(mm) | >5 | 19 (50.0) | 7 (18.4) | 12 (31.6) | 38 (64.4) | Â |
 | ND | 25 - | 11 - | 24 - | 60 - |  |
 | Positive | 15 (40.5) | 6 (16.2) | 16 (43.2) | 37 (59.7) |  |
VSI7 | Negative | 12 (48.0) | 3 (12.0) | 10 (40.0) | 25 (40.3) | 0.83 |
 | ND | 25 - | 11 - | 21 - | 57 - |  |
RESECTION | Positive | 7 (63.6) | 1 (9.1) | 3 (27.3) | 11 (19.3) | Â |
MARGINS7 | Negative | 19 (41.3) | 8 (17.4) | 19 (41.3) | 46 (80.7) | 0.49 |
 | ND | 26 - | 11 - | 25 - | 65 - |  |
 | Negative | 20 (47.6) | 4 (9.5) | 18 (42.9) | 42 (49.4) |  |
LN STATUS8 | Positive | 18 (41.9) | 8 (18.6) | 17 (39.5) | 43 (50.6) | 0.55 |
 | ND | 14 - | 8 - | 12 - | 34 - |  |
 | NED | 34 42.5) | 13 (16.3) | 33 (41.3) | 80 (67.2) |  |
STATUS9 | DOD | 18 46.2) | 7 (17.9) | 14 (35.9) | 39 (32.8) | 0.87 |